Covalent display of oligosaccharide arrays in microtiter plates

Journal of the American Chemical Society
Marian C BryanChi-Huey Wong

Abstract

A covalent array for the display of complex oligosaccharides in microtiter plates has been developed. This strategy is conducive to the display of carbohydrates to proteins of interest such as lectins and antibodies, including the broadly neutralizing antibody 2G12 against HIV envelope oligomannose and can be cleaved from the surface for further characterization by mass spectrometry. The system was used to probe the multivalent interaction of 2G12 with an optimal epitope (Kd 0.1 muM).

References

Jul 4, 2001·Nucleic Acids Research·K LindroosA C Syvänen
Oct 25, 2001·Journal of the American Chemical Society·T HaselhorstT Peters
May 2, 2002·Chemistry & Biology·Benjamin T Houseman, Milan Mrksich
Jun 25, 2002·Chemistry & Biology·Marian C BryanChi-Huey Wong
Sep 5, 2002·Journal of the American Chemical Society·Paul T NyffelerChi-Huey Wong
Nov 28, 2002·Journal of the American Chemical Society·Fabio FazioChi-Huey Wong
Mar 5, 2004·Chembiochem : a European Journal of Chemical Biology·Sujiet PuthenveetilPeter A Beal

❮ Previous
Next ❯

Citations

Jan 7, 2005·Chemistry : a European Journal·Injae ShinMyung-ryul Lee
Nov 18, 2006·Applied Microbiology and Biotechnology·Gang-Liang HuangPeng-George Wang
Apr 23, 2013·Journal of Chromatography. a·Qianying ShengXinmiao Liang
Oct 12, 2010·Bioconjugate Chemistry·Avijit Kumar AdakAlexander Wei
Jun 16, 2005·Journal of the American Chemical Society·Neal K DevarajChristopher E D Chidsey
Nov 3, 2010·Journal of the American Chemical Society·Guoting QinChengzhi Cai
Mar 8, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·James P CollmanChristopher E D Chidsey
Jun 15, 2007·Chemical Communications : Chem Comm·Zhimou GuoXinmiao Liang
Sep 20, 2008·Chemical Communications : Chem Comm·Sungjin ParkInjae Shin
Sep 20, 2008·Chemical Communications : Chem Comm·Nicolas LaurentSabine L Flitsch
Jun 9, 2009·Chemical Communications : Chem Comm·Tomonari TanakaShin-Ichiro Shoda
Oct 27, 2010·Chemical Communications : Chem Comm·M Carmen GalanClaire Bernard
Apr 16, 2011·Chemical Communications : Chem Comm·Hao WuShao Q Yao
Aug 12, 2008·Proceedings of the National Academy of Sciences of the United States of America·Cheng-Chi WangChi-Huey Wong
Jul 22, 2005·Immunology and Cell Biology·Fernando J IrazoquiGustavo A Nores
Apr 13, 2010·Annual Review of Biochemistry·Laura L Kiessling, Rebecca A Splain
Apr 8, 2011·Annual Review of Biochemistry·Cory D Rillahan, James C Paulson
Nov 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ola BlixtJames C Paulson
Dec 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·Cheng-Yuan HuangChi-Huey Wong
Sep 22, 2005·Proceedings of the National Academy of Sciences of the United States of America·Daniel A CalareseIan A Wilson
Feb 4, 2014·Current Opinion in Chemical Biology·Ola Blixt, Ulrika Westerlind
Feb 19, 2014·Current Opinion in Chemical Biology·Andreas GeissnerPeter H Seeberger
Jan 23, 2016·Chemical Reviews·Vinod K TiwariXi Chen
Mar 8, 2008·Journal of Mass Spectrometry : JMS·Yuki ShioiriOsamu Kanie
Feb 11, 2005·Current Opinion in Chemical Biology·Nicola L Pohl
Aug 5, 2008·Bioelectrochemistry·Miyuki ChikaeEiichi Tamiya
Jun 17, 2016·Annual Review of Analytical Chemistry·Andreas Geissner, Peter H Seeberger
Dec 22, 2004·Chemistry & Biology·Lara K Mahal
Apr 2, 2008·Expert Review of Vaccines·Oyindasola Oyelaran, Jeffrey C Gildersleeve
Jul 19, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Simon S ParkJacquelyn Gervay-Hague
Jan 18, 2006·Chembiochem : a European Journal of Chemical Biology·Jürgen SeibelBodo Schmalbruch
Apr 19, 2012·Chemistry : a European Journal·Henning S G BeckmannValentin Wittmann
May 29, 2012·Chemistry, an Asian Journal·Hiromichi FujiokaKenichi Murai
Mar 31, 2005·Chembiochem : a European Journal of Chemical Biology·Kanoelani T PilobelloLara K Mahal
Sep 30, 2010·Chemistry : a European Journal·Sonia SernaNiels-Christian Reichardt
Apr 28, 2006·Angewandte Chemie·Joseph C ManimalaJeffrey C Gildersleeve

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.