Covalent Post-Assembly Modification: A Synthetic Multipurpose Tool in Supramolecular Chemistry

ChemPlusChem
Haoxiang ZengDerrick A Roberts

Abstract

The use of covalent post-assembly modification (PAM) in supramolecular chemistry has grown significantly in recent years, to the point where PAM is now a versatile synthesis tool for tuning, modulating, and expanding the functionality of self-assembled complexes and materials. PAM underpins supramolecular template-synthesis strategies, enables modular derivatization of supramolecular assemblies, permits the covalent 'locking' of unstable structures, and can trigger controlled structural transformations between different assembled morphologies. This Review discusses key examples of PAM spanning a range of material classes, including discrete supramolecular complexes, self-assembled soft nanostructures and hierarchically ordered polymeric and framework materials. As such, we hope to highlight how PAM has continued to evolve as a creative and functional addition to the synthetic chemist's toolbox for constructing bespoke self-assembled complexes and materials.

References

Dec 6, 2001·Advanced Drug Delivery Reviews·A RöslerH A Klok
Dec 20, 2002·Angewandte Chemie·Stuart J RowanJ Fraser Stoddart
Apr 20, 2005·Accounts of Chemical Research·Makoto FujitaBruno Therrien
Mar 15, 2006·Chemistry : a European Journal·Marie HutinJonathan R Nitschke
May 31, 2007·Chemical Society Reviews·Jim A Thomas
Apr 2, 2008·Journal of the American Chemical Society·Amit SagiDoron Shabat
Aug 16, 2008·Journal of the American Chemical Society·Liang ZhaoPeter J Stang
Dec 2, 2008·Angewandte Chemie·Marc A GauthierHarm-Anton Klok
Apr 23, 2009·Chemical Society Reviews·Zhenqiang Wang, Seth M Cohen
Jun 11, 2010·Proceedings of the National Academy of Sciences of the United States of America·Steven D Perrault, Warren C W Chan
Aug 24, 2010·Nature Chemistry·Jonathan E Beves, David A Leigh
Oct 6, 2010·Angewandte Chemie·Michael J WiesterChad A Mirkin
Jan 7, 2011·Nature·Melanie C O'SullivanHarry L Anderson
Jul 1, 2009·Nature Chemistry·Krzysztof Matyjaszewski, Nicolay V Tsarevsky
Apr 5, 2011·Angewandte Chemie·Lilit Aboshyan-SorghoClaude Piguet
Feb 18, 2009·Macromolecular Rapid Communications·Adam BlanazsAnthony J Ryan
Aug 23, 2011·Journal of the American Chemical Society·Shinji SugiharaAndrew L Lewis
Nov 26, 2011·Chemical Society Reviews·Ali CoskunBartosz A Grzybowski
Jan 4, 2012·Chemistry : a European Journal·Maria E GallinaPaola Ceroni
Jan 27, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Ye ZhangBing Xu
Jul 17, 2012·Chemical Society Reviews·Michael D Ward, Paul R Raithby
Aug 25, 2012·Journal of the American Chemical Society·Rajesh Chakrabarty, Peter J Stang
Sep 8, 2012·Food Chemistry·Cristiane Patrícia de OliveiraAntônio Manoel Maradini Filho
Oct 12, 2012·Organic & Biomolecular Chemistry·Miguel Á Alemán García, Nick Bampos
Nov 30, 2012·Accounts of Chemical Research·Graeme T Spence, Paul D Beer
Dec 5, 2012·Angewandte Chemie·Muxin HanGuido H Clever
Jan 5, 2013·Chemical Communications : Chem Comm·Tanya K RonsonJonathan R Nitschke
Jan 31, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Mallesh PandralaJ Grant Collins
Feb 21, 2013·Angewandte Chemie·Markus W SchneiderMichael Mastalerz
May 29, 2013·Advanced Materials·Miao-Ping ChienNathan C Gianneschi
Jun 14, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sreedhar K VellasJames D Crowley
Jun 22, 2013·Accounts of Chemical Research·Timothy R CookKi-Whan Chi
Aug 14, 2013·Chemistry : a European Journal·Derrick A RobertsSébastien Perrier
Dec 19, 2013·Chemical Communications : Chem Comm·Michael C YoungRichard J Hooley
Jan 1, 2014·Angewandte Chemie·Jesús MosqueraJonathan R Nitschke

❮ Previous
Next ❯

Citations

Jan 12, 2021·Chemistry, an Asian Journal·Timothy N ForderDerrick A Roberts
Feb 23, 2021·Chemical Communications : Chem Comm·Adrian W Markwell-HeysWitold M Bloch
Apr 21, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Shigehisa Akine
Jun 12, 2021·Frontiers in Chemistry·Matthew L SchneiderWitold M Bloch
Jul 23, 2021·Inorganic Chemistry·Erica GiraldiKay Severin
Nov 26, 2020·Chemical Reviews·Edmundo G PercásteguiJonathan R Nitschke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.