Coverage and accuracy of myeloproliferative and myelodysplastic neoplasms in the Finnish Cancer Registry

Acta Oncologica
Maarit K LeinonenNea Malila

Abstract

Background Registration of haematological malignancies presents specific challenges, and a wide range of data is required to ensure case ascertainment and proper classification of these diseases. We studied the data quality of myeloproliferative and myelodysplastic neoplasms in the Finnish Cancer Registry (FCR), comparing information with hospital discharges. Material and methods Hospital discharges (HILMO) in 2007-2013 including diagnostic codes of myeloproliferative and myelodysplastic neoplasms were extracted. Patients were individually linked to the FCR database for all haematological malignancies registered in 1953-2013. Coverage and accuracy of the FCR and agreement between registers was estimated. Results In total 5289 individuals were retrieved from two registers. Of these, 1406 were common, 1080 only found in the FCR and 2803 only in the HILMO. Coverage of myeloproliferative and myelodysplastic neoplasms in the FCR was 47.0% (95% CI 45.7-48.4%). Almost one quarter of the registrations in the FCR was based on a death certificate only. The accuracy of diagnosis was 51.4% (95% CI 49.4-53.3%), but it varied substantially by disease category. Kappa statistic for agreement between registers was excellent (0.83, 95% CI 0.80-0...Continue Reading

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Citations

Dec 12, 2017·Acta Oncologica·Eero PukkalaGiske Ursin
Jul 11, 2019·Acta Oncologica·M JokelaL M Madanat-Harjuoja
Jul 14, 2020·Acta Oncologica·Janne PitkäniemiUNKNOWN METCA Study Group
May 19, 2021·British Journal of Haematology·Rosa RönkköJanne Pitkäniemi

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