COVID-19 - Important considerations for developing and using a vaccine.

Human Vaccines & Immunotherapeutics
Inayat Ur RahmanElsayed Fathi Abd Allah

Abstract

The novel coronavirus SARS-CoV-2 after emerging in China has caused a global pandemic that is risking the lives of millions. COVID-19 has spread across the world at a very rapid rate raising concerns of capacity limitations and lack of unified responses at the global level, particularly from the world's most developed countries. The spread of further infection has been curtailed by lockdown and mass social distancing that has been enforced in most parts of the world. There are no clinical data yet suggesting that any available candidate vaccine will be effective for COVID-19 which will be a critical need for eventually preventing this disease. Extensive research is underway with some success in identification of monoclonal antibodies from COVID-19 recovered patients, which may inform on vaccine development. The clinical evaluations of COVID-19 vaccines need to follow standardized protocols that are essential for safeguarding humans. In absence of a vaccine or a widely available effective therapy, quarantine and other preventive measures are essential in curtailing the risk of pandemic spread.

References

Aug 25, 2016·NPJ Vaccines·David W C BeasleyJason E Comer
Mar 4, 2020·JAMA : the Journal of the American Medical Association·Barnaby Edward YoungUNKNOWN Singapore 2019 Novel Coronavirus Outbreak Research Team
Mar 18, 2020·The New England Journal of Medicine·Neeltje van DoremalenVincent J Munster
Mar 19, 2020·The New England Journal of Medicine·Bin CaoChen Wang
Jan 14, 2021·Transactions of the Royal Society of Tropical Medicine and Hygiene·Zachary Barnett-HowellAhmed Mushfiq Mobarak

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Citations

May 3, 2021·Patient Safety in Surgery·Pratibha Anand, Vincent P Stahel

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