COVID 19 and diabetes: An endocrinologist's perspective

Journal of Family Medicine and Primary Care
Kishore K BeheraAshoka Mahapatra

Abstract

The clinical manifestation of COVID-19 is diverse, oscillating from mild flu-like symptoms to more severe outcome, such as acute respiratory distress syndrome, multiple organ failure, and death. Advanced age and comorbidities, such as diabetes mellitus, high blood pressure, and history of cerebrovascular accidents are reported to have worse outcome. Chronic inflammation by cytokine storm and direct insult to pancreatic by COVID-19 might be postulated mechanisms of inducing or deteriorating diabetes. Individualized patient-centric treatment and optimal blood sugar control should be made based on disease severity, presence of comorbid condition, and complications related to diabetes, age, and other risk factors. Recent clinical trials have shown some hope to anti-interleukin antibody as a potential therapeutic option against COVID-19 especially in people with severe illness.

References

Jun 9, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·J K YangJ C N Chan
Mar 15, 2020·The Lancet. Respiratory Medicine·Lei FangMichael Roth
Mar 17, 2020·Diabetes & Metabolic Syndrome·Ritesh GuptaAnoop Misra
Mar 18, 2020·Diabetes Research and Clinical Practice·Aihong WangJianwen Gu
Mar 21, 2020·Lancet·Puja MehtaUNKNOWN HLH Across Speciality Collaboration, UK
Apr 1, 2020·The New England Journal of Medicine·Muthiah VaduganathanScott D Solomon
Apr 2, 2020·Diabetes/metabolism Research and Reviews·Weina GuoDesheng Hu
Apr 2, 2020·Diabetes/metabolism Research and Reviews·Ernesto Maddaloni, Raffaella Buzzetti
Apr 4, 2020·Nature Reviews. Endocrinology·Stefan R BornsteinBernhard O Boehm
Apr 14, 2020·The Journal of Infection·Qing YeJianhua Mao

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Citations

May 22, 2021·Journal of Family Medicine and Primary Care·Anil Kumar Goel, Seema Shah

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