COVID-19 antibody therapeutics tracker: a global online database of antibody therapeutics for the prevention and treatment of COVID-19.

Antibody Therapeutics
Lifei YangMitchell Ho

Abstract

Facing the COVID-19 global healthcare crisis, scientists worldwide are collaborating to develop prophylactic and therapeutic interventions against the disease. Antibody therapeutics hold enormous promise for the treatment of COVID-19. In March 2020, the Chinese Antibody Society, in collaboration with The Antibody Society, initiated the "COVID-19 Antibody Therapeutics Tracker" ("Tracker") (https://chineseantibody.org/covid-19-track/) program to track the antibody-based COVID-19 interventions in preclinical and clinical development globally. The data are collected from the public domain and verified by volunteers on an ongoing basis. Here, we present exploratory data analyses and visualization to demonstrate the latest trends of COVID-19 antibody development, based on data for over 150 research and development programs and molecules included in the "Tracker" as of 8 August 2020. We categorized the data mainly by their targets, formats, development status, developers and country of origin. Although details are limited in some cases, all of the anti-SARS-CoV-2 antibody candidates appear to target the viral spike protein (S protein), and most are full-length monoclonal antibodies. Most of the current COVID-19 antibody therapeutic ca...Continue Reading

References

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Jul 9, 2020·BioRxiv : the Preprint Server for Biology·Leonid YurkovetskiyJeremy Luban

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Citations

Dec 16, 2020·MAbs·Marco TuccoriDaniele Focosi
Jan 21, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Manman LiuYangzhong Liu
Dec 31, 2020·Journal of Molecular Cell Biology·Liu Daisy LiuFei-Long Meng
Jan 7, 2021·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Bhavesh D KevadiyaHoward E Gendelman
Mar 9, 2021·Frontiers in Medicine·Candice Laverne HendricksMichael Sean Pepper
Mar 25, 2021·Biological Chemistry·Bernhard ValldorfStefan Zielonka
Apr 30, 2021·Antibody Therapeutics·Yaping Sun, Mitchell Ho
May 1, 2021·Viruses·Aeron C Hurt, Adam K Wheatley
May 1, 2021·Antibody Therapeutics·Donovan GuttieresStacy L Springs
Jun 1, 2021·Frontiers in Molecular Biosciences·Miao Mei, Xu Tan
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marco A Almaraz-GirónSandra L Castañón-Alonso
Jul 27, 2021·World Journal of Clinical Cases·Ceylan Polat, Koray Ergunay
Jul 29, 2021·Clinical Microbiology Reviews·Kaiming TaoRobert W Shafer
Apr 16, 2021·British Journal of Clinical Pharmacology·Jasmine DavdaPatrick F Smith
Sep 3, 2021·The Cochrane Database of Systematic Reviews·Nina KreuzbergerNicole Skoetz

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Software Mentioned

COV2
WordPress
REGN
SQLite
Python
Celltrion
WPDatatable Plugin

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