COVID-19 fatality prediction in people with diabetes and prediabetes using a simple score upon hospital admission

Diabetes, Obesity & Metabolism
Harald SourijCOVID-19 in diabetes in Austria study group

Abstract

To assess predictors of in-hospital mortality in people with prediabetes and diabetes hospitalized for COVID-19 infection and to develop a risk score for identifying those at the greatest risk of a fatal outcome. A combined prospective and retrospective, multicentre, cohort study was conducted at 10 sites in Austria in 247 people with diabetes or newly diagnosed prediabetes who were hospitalized with COVID-19. The primary outcome was in-hospital mortality and the predictor variables upon admission included clinical data, co-morbidities of diabetes or laboratory data. Logistic regression analyses were performed to identify significant predictors and to develop a risk score for in-hospital mortality. The mean age of people hospitalized (n = 238) for COVID-19 was 71.1 ± 12.9 years, 63.6% were males, 75.6% had type 2 diabetes, 4.6% had type 1 diabetes and 19.8% had prediabetes. The mean duration of hospital stay was 18 ± 16 days, 23.9% required ventilation therapy and 24.4% died in the hospital. The mortality rate in people with diabetes was numerically higher (26.7%) compared with those with prediabetes (14.9%) but without statistical significance (P = .128). A score including age, arterial occlusive disease, C-reactive protein, e...Continue Reading

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Citations

Feb 10, 2021·Journal of Diabetes·Thirunavukkarasu Sathish, Nirmala Devi Chandrasekaran
Jul 6, 2021·Diabetes & Metabolic Syndrome·Nirmala Devi ChandrasekaranThirunavukkarasu Sathish
Jul 27, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Milena S MarcolinoCarisi A Polanczyk
Oct 3, 2021·Cardiovascular Diabetology·Leszek CzupryniakGuntram Schernthaner

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