COVID-19 (Novel Coronavirus 2019) - recent trends

European Review for Medical and Pharmacological Sciences
S KannanK Hemalatha

Abstract

The World Health Organization (WHO) has issued a warning that, although the 2019 novel coronavirus (COVID-19) from Wuhan City (China), is not pandemic, it should be contained to prevent the global spread. The COVID-19 virus was known earlier as 2019-nCoV. As of 12 February 2020, WHO reported 45,171 cases and 1115 deaths related to COVID-19. COVID-19 is similar to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) virus in its pathogenicity, clinical spectrum, and epidemiology. Comparison of the genome sequences of COVID-19, SARS-CoV, and Middle East Respiratory Syndrome coronavirus (MERS-CoV) showed that COVID-19 has a better sequence identity with SARS-CoV compared to MERS CoV. However, the amino acid sequence of COVID-19 differs from other coronaviruses specifically in the regions of 1ab polyprotein and surface glycoprotein or S-protein. Although several animals have been speculated to be a reservoir for COVID-19, no animal reservoir has been already confirmed. COVID-19 causes COVID-19 disease that has similar symptoms as SARS-CoV. Studies suggest that the human receptor for COVID-19 may be angiotensin-converting enzyme 2 (ACE2) receptor similar to that of SARS-CoV. The nucleocapsid (N) protein of COVID-19 has nearly 90...Continue Reading

Citations

Apr 21, 2020·Military Medical Research·Jing-Chun SongUNKNOWN People’s Liberation Army Professional Committee of Critical Care Medicine, Chinese Society on Thrombosis and Haemostasis
Aug 9, 2020·International Journal of Environmental Research and Public Health·Hossein HozhabriMeysam Sarshar
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Oct 20, 2020·Frontiers in Public Health·Ashwani KumarAnamika Dubey
Oct 15, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Mukesh Kumar, Ajit Kumar Thakur
Feb 13, 2021·World Journal of Radiology·Md Abdul Alim Al-BariMd Kudrat-E Zahan
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Jan 19, 2021·Bulletin of the National Research Centre·Ghadha Ibrahim Fouad
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Feb 25, 2021·Environmental Science and Pollution Research International·FengSheng ChienMuhammad Raza
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Jun 4, 2021·International Journal of General Medicine·Hui JiaShuyue Xia
Jun 22, 2021·Frontiers in Immunology·Xiang-Zhi FangYou Shang
Jun 22, 2021·Frontiers in Medicine·Arjun SharmaMarkus Bosmann
Jul 23, 2021·Medical & Biological Engineering & Computing·Heba M Afify, Muhammad S Zanaty
Sep 4, 2021·Intensive Care Medicine Experimental·Vadim LesanTorben Rixecker

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