COVID-19 Outbreak in an Urban Hemodialysis Unit

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Kevin YauRon Wald

Abstract

Hemodialysis patients are at increased risk for coronavirus disease 2019 (COVID-19) transmission due in part to difficulty maintaining physical distancing. Our hemodialysis unit experienced a COVID-19 outbreak despite following symptom-based screening guidelines. We describe the course of the COVID-19 outbreak and the infection control measures taken for mitigation. Retrospective cohort study. 237 maintenance hemodialysis patients and 93 hemodialysis staff at a single hemodialysis center in Toronto, Canada. Universal screening of patients and staff for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The primary outcome was detection of SARS-CoV-2 in nasopharyngeal samples from patients and staff using reverse transcriptase-polymerase chain reaction (RT-PCR). Descriptive statistics were used for clinical characteristics and the primary outcome. 11 of 237 (4.6%) hemodialysis patients and 11 of 93 (12%) staff members had a positive RT-PCR test result for SARS-CoV-2. Among individuals testing positive, 12 of 22 (55%) were asymptomatic at time of testing and 7 of 22 (32%) were asymptomatic for the duration of follow-up. One patient was hospitalized at the time of SARS-CoV-2 infection and 4 additional patients with posi...Continue Reading

Citations

Dec 5, 2020·Hemodialysis International·Hamid Tayebi KhosroshahiTaghi Fadaei Haggi
Mar 14, 2021·Clinical Journal of the American Society of Nephrology : CJASN·Matthew J Oliver, John H Crabtree
Mar 12, 2021·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ben StoreyKatherine Bull
Jun 3, 2021·International Journal of Environmental Research and Public Health·Luis D'MarcoJosé Luis Gorriz
Jun 27, 2021·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·José Jesús BrosetaFrancisco Maduell
Jul 9, 2021·PLoS Computational Biology·Hankyu JangSriram V Pemmaraju
Jul 18, 2021·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Fernanda Salomão Gorayeb-PolacchiniMario Abbud-Filho
Aug 12, 2021·Proceedings of the National Academy of Sciences of the United States of America·Pratha SahAlison P Galvani
Aug 17, 2021·Canadian Journal of Kidney Health and Disease·Daphne C SniekersMatthew J Oliver
Aug 29, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Erica C BjornstadDaniel I Feig

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