COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis

Journal of Medical Virology
Long-Quan LiYuping Wang

Abstract

The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 52% (95% CI [0.34,0.70]), and the fatality rate was 5% (95% CI [0.01,0.11]).

References

Dec 7, 2013·The Clinical Respiratory Journal·Xiao Fei WangMin Zhou
Mar 27, 2015·Clinical Microbiology Reviews·Jasper F W ChanKwok-Yung Yuen
Jun 30, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Alaa Badawi, Seung Gwan Ryoo
Apr 5, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Rudragouda ChannappanavarStanley Perlman
Oct 1, 2017·Clinical Reviews in Allergy & Immunology·Sébastien JaillonCecilia Garlanda
Oct 21, 2017·Respirology : Official Journal of the Asian Pacific Society of Respirology·Yudong Yin, Richard G Wunderink
Jan 17, 2019·Viruses·Zhiqi SongChuan Qin
Jan 25, 2020·The New England Journal of Medicine·Na ZhuUNKNOWN China Novel Coronavirus Investigating and Research Team
Jan 30, 2020·The New England Journal of Medicine·Qun LiZijian Feng
Feb 8, 2020·JAMA : the Journal of the American Medical Association·De ChangLokesh Sharma
Feb 8, 2020·JAMA : the Journal of the American Medical Association·Dawei WangZhiyong Peng
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19

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Citations

Apr 30, 2020·Journal of Internal Medicine·Giuseppe PascarellaFelice Eugenio Agrò
Mar 28, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas C HanffAmir M Mohareb
May 2, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L C PoonF Prefumo
May 19, 2020·American Journal of Physiology. Endocrinology and Metabolism·Johnny S YounisKarl Skorecki
Apr 11, 2020·Journal of Medical Virology·Giuseppe LippiBrandon M Henry
Jun 3, 2020·International Journal of Environmental Research and Public Health·Maria Grazia CagettiGuglielmo Campus
Mar 30, 2020·International Journal of Laboratory Hematology·Sabrina BuoroStefano Fagiuoli
May 21, 2020·Clinical Chemistry and Laboratory Medicine : CCLM·Emmanuel J Favaloro, Jecko Thachil
Jun 11, 2020·Journal of Clinical Medicine·Jacek BajRyszard Maciejewski
May 27, 2020·The American Journal of Gastroenterology·Federica MelazziniAntonio Di Sabatino
Jul 3, 2020·European Heart Journal·Carina Blomström-Lundqvist
May 30, 2020·Clinical Reviews in Allergy & Immunology·Shuang LiuSun Ying
Jul 15, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Luca D'AscanioArianna Di Stadio
Jun 11, 2020·Clinics·Lucas Souto NacifLuiz Carneiro D'Albuquerque
Jul 16, 2020·Headache·Jesús Porta-EtessamJorge Matías-Guiu
Jun 25, 2020·Clinics·Helena BelliniJosé Gallucci-Neto
Jul 21, 2020·Asian Cardiovascular & Thoracic Annals·Ahmed Ma BakryHysam Abdelmohty
Jul 30, 2020·Acta Clinica Belgica·Jiajia QuYuwen Xue
Jul 19, 2020·European Journal of Clinical Investigation·Yin ZhangJihong Dai
Jul 19, 2020·Andrology·Vassilios PapadopoulosMary Samplaski
Jun 12, 2020·The American Journal of Tropical Medicine and Hygiene·Ashraf O E AhmedMouhand F H Mohamed
Aug 21, 2020·PloS One·Ross McQueenieBarbara I Nicholl
Aug 25, 2020·Thrombosis and Haemostasis·Upendra K KatneniChava Kimchi-Sarfaty
Jun 25, 2020·Emergency Medicine Australasia : EMA·Biswadev MitraPeter A Cameron
Aug 30, 2020·Journal of Clinical Laboratory Analysis·Qian LiuFumeng Yang
Sep 23, 2020·American Journal of Speech-language Pathology·José VergaraLucia Figueiredo Mourão
Jul 18, 2020·Medwave·Francisca Verdugo-PaivaGabriel Rada
Aug 8, 2020·Medwave·Eduard BaladiaGabriel Rada
Sep 25, 2020·International Journal of Dermatology·Irune Méndez MaestroJesús Gardeazabal García
Sep 29, 2020·Journal of Cardiac Surgery·Dimitrios C Iliopoulos
Oct 1, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Agnaldo José LopesRoberto Mogami
Aug 12, 2020·Rinshō shinkeigaku = Clinical neurology·Keisuke Suzuki
Sep 19, 2020·Aging Clinical and Experimental Research·Andrea TicinesiTiziana Meschi

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Methods Mentioned

BETA
bronchoalveolar lavage

Software Mentioned

STATA
Excel

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