COVID-19-Related Intracerebral Hemorrhage

Frontiers in Aging Neuroscience
Valentin PavlovGjumrakch Aliev

Abstract

Intracerebral hemorrhage (ICH) is a common and severe neurological disorder and is associated with high rates of mortality and morbidity. ICH is associated with old age and underlying conditions such as hypertension and diabetes mellitus. The COVID-19 pandemic is associated with neurological symptoms and complications including ICH. For instance, the mechanisms by which COVID-19 may contribute to hemorrhagic stroke may include both depletion of angiotensin converting enzyme 2 (ACE2) receptor and overactive immune response. In this study, we herein report three patients (0.25%) out of 1200 admissions with COVID-19 to our center between 1 May and August 4, 2020, who developed ICH. In addition, we will briefly discuss the possible pathophysiological mechanisms of COVID-19 infection in patients with ICH.

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Citations

Feb 15, 2021·Reviews in the Neurosciences·Giovanni FrisulloPaolo Calabresi
Apr 13, 2021·Brain, Behavior, & Immunity Health·Francisco J Barrantes
May 14, 2021·British Journal of Neurosurgery·Mohammed Maan Al-SalihiMd Moshiur Rahman
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Aug 27, 2021·The International Journal of Neuroscience·Zeina Hassan OusseiranWafaa Takash Chamoun

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