Cranial hemophilic pseudotumor: case report

Neurosurgery
K B Sim, S K Hong

Abstract

Hemophilic pseudotumor is a rare complication of hemophilia, occurring in 1 to 2% of patients with severe hemophilia. Its principal sites of occurrence are the long bones and the pelvis. Only one case of this tumor occurring in the cranium has been previously reported. We report a case of cranial hemophilic pseudotumor involving the diploe of the right parietal vault. A 29-year-old man with severe hemophilia (Factor VIII, 0.8% of normal activity) presented with an unsightly scalp protrusion measuring 5 x 5 x 2 cm and tingling discomfort in the left arm. About 5 years before admission, he noted a walnut-sized, nontender mass in the right parietal area that had enlarged slightly after minor head trauma. Tingling discomfort developed as the manifestation of the compression of the parietal lobe in the 2 to 3 months after the head trauma. Under proper factor replacement therapy, surgery was undertaken for excision and tissue diagnosis. Histological examination of the content in the diploe revealed old blood coagulum. Postoperatively, the tingling discomfort in the arm resolved completely. To our knowledge, this is the second case of the cranial hemophilic pseudotumor in the English literature. Diagnosis and management of cranial hem...Continue Reading

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Citations

Oct 26, 2012·Neurologia Medico-chirurgica·Daina KashiwazakiKiyohiro Houkin
Jun 20, 2014·Journal of Pediatric Hematology/oncology·Claire L AndersonJoanna A Davis
Apr 21, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Nanda PaiLopa Mehta
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Jul 10, 2014·The Journal of Craniofacial Surgery·Qingsheng XuYiping Feng
Jun 8, 2017·The Journal of Bone and Joint Surgery. American Volume·Jiliang ZhaiYan-Yan Bian
Nov 20, 2019·Haemophilia : the Official Journal of the World Federation of Hemophilia·Andrew J DoyleSteve Austin
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Dec 9, 2010·Skeletal Radiology·Giovani Rodrigues BatistaRicardo Karam Kalil
Jul 3, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·A D GuptaD Mahalanabis
Mar 30, 2021·Open Medicine·Kunzhe LinFan Zhang
Jun 18, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Deok-Won LeeYong-Dae Kwon

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