Cranial nerve seven palsy and its influence on meibomian gland function

Ophthalmic Plastic and Reconstructive Surgery
Christopher T ShahAdam S Hassan

Abstract

To investigate a possible relationship between cranial nerve seven (CN VII) palsy and meibomian gland dysfunction. A prospective case series of 16 patients with unilateral CN VII palsy was evaluated for meibomian gland function. Main outcome measures included the Sunnybrook Facial Grading System for CN VII palsy and a modified version of a noncontact, noninvasive meibomian gland evaluation by Arita et al., Unaffected contralateral eyes were used as the control group for comparison. Sixteen affected eyes were evaluated. The mean Sunnybrook Facial Grading System composite score was 34.19 ± 24 (score = -15 to 100; maximum function = 100). A paired samples t test between affected and unaffected eyes demonstrated a significant difference between mean values for tear break-up time, eyelid abnormality, meiboscore for upper eyelid, meiboscore for lower eyelid, combined meiboscore, and digital pressure. No significant difference was found for superficial punctate keratopathy nor Schirmer's test. A Pearson product-moment correlation coefficient found a significant negative correlation between the Sunnybrook Facial Grading System composite score and all aspects of meibomian gland function, except for the upper eyelid meiboscore, which onl...Continue Reading

References

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Citations

Jul 8, 2014·The Ocular Surface·Stephanie M Cox, Jason J Nichols
Apr 4, 2015·Current Eye Research·Ting WanYingying Zhao
Apr 11, 2015·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Joana PortelinhaJoão Marques Costa
Aug 21, 2013·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Ryan J WiseRichard C Allen
Aug 8, 2014·Ophthalmic Plastic and Reconstructive Surgery·Yasuhiro Takahashi, Hirohiko Kakizaki
Jul 10, 2018·Current Opinion in Ophthalmology·Richard C Allen
Aug 15, 2013·Current Opinion in Ophthalmology·Charles Kim, Gary J Lelli
Jul 13, 2013·Current Opinion in Ophthalmology·Richard C Allen
Sep 13, 2014·Ophthalmic Plastic and Reconstructive Surgery·David T TseBrian C Tse
Sep 1, 2013·Asia-Pacific Journal of Ophthalmology·Santosh G Honavar, Fairooz P Manjandavida
Jun 12, 2019·Acta Ophthalmologica·We Fong SiahRaman Malhotra

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