PMID: 332131Sep 1, 1977Paper

Creutzfeldt-Jakob disease; clinical, histopathological and electron microscopy study of a case

Arquivos de neuro-psiquiatria
J Guidugli NetoL C Mattosinso-Franca

Abstract

The case of a patient 53 years old that had a picture of cortical impairment and pyramidal disfunction, leading in 6 months to acinetic mutism is reported. The histopathology lead to the diagnostic of Creutzeldt-Jakob disease, with neuronal loss, gliosis and status spongiosus. The electron-microscopic examination showed that the status spongiosus was due to cellular processes, some having vesicular bodies sugestive of pre-synaptic vesicles.

References

Feb 1, 1974·Journal of Neurology, Neurosurgery, and Psychiatry·H AdamsA M Shenkin
Jan 1, 1973·Brain : a Journal of Neurology·R RoosC J Gibbs
Jan 1, 1970·Brain : a Journal of Neurology·A Bignami, L S Forno
Jul 1, 1969·Journal of Neuropathology and Experimental Neurology·P W LampertD C Gajdusek
Jan 1, 1970·Brain : a Journal of Neurology·D C GajdusekJ Meyer

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Citations

Mar 1, 1987·Arquivos de neuro-psiquiatria·J A KouyoumdjianR de B Costa
Jun 1, 1991·Arquivos de neuro-psiquiatria·A J Caraballo

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