PMID: 9190535Mar 29, 1997Paper

Creutzfeldt-Jakob disease; one year later

Nederlands tijdschrift voor geneeskunde
W A van Gool, P H Meijerink

Abstract

During the last year the knowledge of the transmission of prion diseases has increased. New diagnostic methods were developed: investigation of cerebrospinal fluid for the 14-3-3 protein and tonsillar biopsy to detect protease resistant prion protein. Indirect evidence of a causal relation between new variant Creutzfeldt-Jakob disease (nvCJ) and bovine spongiform encephalopathy (BSE) is accumulating, although epidemiological data do not indicate that the incidence of CJ is increasing.

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