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CRISPR/Cas9-mediated gene deletion of the ompA gene in symbiotic Cedecea neteri impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

PLoS Neglected Tropical Diseases

Dec 4, 2019

Shivanand HegdeGrant L Hughes

Abstract

Symbiotic bacteria are pervasive in mosquitoes and their presence can influence many host phenotypes that affect vectoral capacity. While it is evident that environmental and host genetic factors contribute in shaping the microbiome of mosquitoes, we have a poor understanding regarding ...read more

Mentioned in this Paper

Dengue Fever
Biological Markers
In Vivo
Outer Membrane
Genome
Genes
CRISPR-Cas Systems
Gene Editing
Shared Paranoid Disorder
Gene Deletion
43
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CRISPR/Cas9-mediated gene deletion of the ompA gene in symbiotic Cedecea neteri impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

PLoS Neglected Tropical Diseases

Dec 4, 2019

Shivanand HegdeGrant L Hughes

PMID: 31790395

DOI: 10.1371/journal.pntd.0007883

Abstract

Symbiotic bacteria are pervasive in mosquitoes and their presence can influence many host phenotypes that affect vectoral capacity. While it is evident that environmental and host genetic factors contribute in shaping the microbiome of mosquitoes, we have a poor understanding regarding ...read more

Mentioned in this Paper

Dengue Fever
Biological Markers
In Vivo
Outer Membrane
Genome
Genes
CRISPR-Cas Systems
Gene Editing
Shared Paranoid Disorder
Gene Deletion
43

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