PMID: 3770286Sep 1, 1986Paper

Criteria for the diagnosis of vaginal candidosis: evaluation of a new latex agglutination test

European Journal of Obstetrics, Gynecology, and Reproductive Biology
E G EvansJ A Carney

Abstract

The value of current diagnostic methods (clinical examination, microscopy, mycological culture) was compared with a new slide latex agglutination (SLA) test for the diagnosis of vaginal candidosis in 224 women attending a genito-urinary medicine clinic. Candida albicans was isolated from 44 (19.6%) of women but just less than half of this number (21) had clinical candidosis. Clinical examination correctly identified 81% of women with candidosis but the predictive value of a positive clinical diagnosis was only 51.5%. Microscopical examination of a Gram-stained vaginal smear was also inaccurate and yeasts were seen in smears from only 42.9% of women with candidosis. Cultures were positive in 95.2% of those with candidosis, but 54.6% of women with positive cultures showed only commensal carriage. Overall, the SLA test was more successful. It was as sensitive (81%) as clinical diagnosis in identifying patients with candidosis but it was more specific (98.5%) than the other diagnostic criteria and had the highest overall test efficiency (96.8%).

References

Apr 1, 1985·Journal of Clinical Pathology·V HopwoodJ A Carney
Feb 1, 1960·A.M.A. Journal of Diseases of Children·C L TASCHDJIANP J KOZINN

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Citations

Jul 16, 1999·Diagnostic Cytopathology·M S ShurbajiW L Sawyer
Mar 1, 1992·Journal of Clinical Pharmacology·B J HorowitzS Ito
Aug 1, 1987·European Journal of Clinical Microbiology·V HopwoodP K Taylor
Jan 1, 1991·Journal of Medical and Veterinary Mycology : Bi-monthly Publication of the International Society for Human and Animal Mycology·W J PikeE G Evans
Oct 2, 2009·Journal of Clinical Microbiology·Agnes Marot-LeblondRaymond Robert
Dec 8, 2006·Sexually Transmitted Infections·D J White, A Vanthuyne
Jun 1, 1987·Genitourinary Medicine·R RajakumarJ A Carney
Dec 1, 1992·Genitourinary Medicine·R J Hay
Feb 1, 1990·Acta Odontologica Scandinavica·I Olsen, A Stenderup
Mar 4, 2000·Journal of Clinical Microbiology·P CarlsonJ Paavonen

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