Critical role of a single position in the -35 element for promoter recognition by Mycobacterium tuberculosis SigE and SigH

Journal of Bacteriology
Taeksun SongRobert N Husson

Abstract

Mycobacterial SigE and SigH both initiate transcription from the sigB promoter, suggesting that they recognize similar sequences. Through mutational and primer extension analyses, we determined that SigE and SigH recognize nearly identical promoters, with differences at the 3' end of the -35 element distinguishing between SigE- and SigH-dependent promoters.

References

Feb 23, 1999·Molecular Microbiology·R ManganelliI Smith
Jun 13, 2002·Proceedings of the National Academy of Sciences of the United States of America·Deepak KaushalWilliam R Bishai
Jul 17, 2007·Molecular Microbiology·Kamakshi SurekaManikuntala Kundu
Oct 16, 2007·Journal of Bacteriology·Diana L WilliamsRobert Husson

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Citations

Apr 24, 2012·Molecular Oral Microbiology·S S YanamandraJ P Lewis
Jan 19, 2016·Biochemical and Biophysical Research Communications·Keon Young KimSangYoun Park
Dec 3, 2009·The FEBS Journal·Preeti SachdevaYogendra Singh
Sep 28, 2017·Molecular BioSystems·A Mallick GuptaS Mandal
Dec 3, 2014·Journal of Bacteriology·Rajdeep BanerjeeJayanta Mukhopadhyay
Jul 4, 2019·Molecular Microbiology·Joo-Hong ParkJung-Hye Roe
Mar 13, 2019·Nature Communications·Lingting LiYu Zhang
Nov 8, 2018·BMC Bioinformatics·Erno LindforsMaria Suarez-Diez
Jun 7, 2018·Pathogens and Disease·Hayden T PaclAdrie J C Steyn

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