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Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.
Blood Brain Barrier
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Alzheimer's Disease: Amyloid Beta
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Blood Brain Barrier Regulation in Health & Disease
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Alzheimer's Disease: APOE
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Atrial Fibrillation
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Alzheimer's Disease: Animal Models
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ApoE Phenotypes
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Blood Brain Barrier Chips
The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.