Criticality accident dosimetry by chromosomal analysis

Radiation Protection Dosimetry
P VoisinR S Brame

Abstract

The technique of measuring the frequency of dicentric chromosomal aberrations in blood lymphocytes was used to estimate doses in a simulated criticality accident. The simulation consisted of three exposures; approximately 5 Gy with a bare source and 1 and 2 Gy with a lead-shielded source. Three laboratories made separate estimates of the doses. These were made by the iterative method of apportioning the observed dicentric frequencies between the gamma and neutron components, taking account of a given gamma/neutron dose ratio, and referring the separated dicentric frequencies to dose-response calibration curves. An alternative method, based on Bayesian ideas, was employed. This was developed for interpreting dicentric frequencies in situations where the gamma/neutron ratio is uncertain. Both methods gave very similar results. One laboratory produced dose estimates close to the eventual exercise reference doses and the other laboratories estimated slightly higher values. The main reason for the higher values was the calibration relationships for fission neutrons.

References

Apr 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·R P Virsik-Peuckert, D Harder
Jul 17, 2003·Radiation Protection Dosimetry·R S Brame, P G Groer

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Citations

Sep 9, 2004·Radiation Protection Dosimetry·B AsselineauUNKNOWN National Council on Radiation Protection and Measurements
Oct 24, 2007·Radiation Protection Dosimetry·Alfredo SernaManuel Canteras
Jul 25, 2009·Radiation Protection Dosimetry·James P McNameeRuth C Wilkins
Jan 1, 2014·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·A C AntunesO Monteiro Gil
Jul 10, 2010·Radiation and Environmental Biophysics·Marcela Maria Pereira de Lemos PintoAdemir Amaral
Aug 24, 2010·Radiation Research·Volodymyr A VinnikovKai Rothkamm
Nov 28, 2013·Radiation Protection Dosimetry·Elizabeth A AinsburyKai Rothkamm
Jan 13, 2010·Health Physics·F N FlegalR C Wilkins
Jan 23, 2016·Radiation and Environmental Biophysics·Antonella BertucciDavid J Brenner
Jun 6, 2018·Radiation and Environmental Biophysics·Iwona SłoneckaKrzysztof W Fornalski

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