Cronkhite-Canada syndrome: a rare case report and literature review

BMC Gastroenterology
Ruifeng ZhaoLiangru Zhu

Abstract

Cronkhite-Canada Syndrome (CCS) is a rare non-inherited disease characterized by gastrointestinal polyposis and ectodermal abnormalities, the estimated incidence is about one per million. Recognizing and curing the disorder face great challenge. This report refers to a Chinese 52 year old man with gastrointestinal symptoms and ectodermal abnormalities. Gastrointestinal symptoms occurred without obvious cause, followed by ectodermal abnormalities after two months. In several hospitals, endoscopy examinations found numerous polypoid lesions in various sizes spreading over the stomach and the entire colon and rectum, histopathological examinations showed inflammatory and adenomatous polyp. In our hospital, both endoscopy and the contrast-enhanced computed tomography (CT) of small intestine showed gastrointestinal polyposis. Gastric antrum and the colon biopsy samples suggested hyperplastic and inflammatory polyp respectively. Endoscopic ultrasonography (EUS) suggested gastric wall thickening. Fujinnon intelligent color enhancement (FICE) revealed that the size of gastric glands pit varied, and vessels were visible. Confocal endoscope showed increased glandular epithelium layers. Magnifying narrow-band imaging endoscopy (ME-NBI) de...Continue Reading

References

Jun 16, 1955·The New England Journal of Medicine·L W CRONKHITE, W J CANADA
Feb 3, 2004·Digestion·Masakazu YashiroKosei Hirakawa
Jun 16, 2005·Southern Medical Journal·Mei QiaoXu Jian-Ming
Feb 16, 2007·Internal Medicine·Masaharu NakayamaKenzaburo Tani
Sep 2, 2011·Digestive Diseases and Sciences·Seth SweetserLisa A Boardman
Jan 18, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N E SamalaviciusH Zažeckis
Nov 1, 2013·Journal of Clinical Gastroenterology·Naoki OhmiyaHidemi Goto
Dec 18, 2013·Journal of the National Comprehensive Cancer Network : JNCCN·Matthew F Kalady
May 9, 2015·Journal of Clinical and Diagnostic Research : JCDR·Subrata Chakrabarti

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Citations

Oct 24, 2017·The American Journal of Dermatopathology·Mati ChuamanochanSiri Chiewchanvit
May 10, 2018·BMJ Case Reports·Maria Pina DoreGiovanni Mario Pes
Dec 14, 2018·Intestinal research·Shuang LiuJi Li
May 28, 2020·The Journal of International Medical Research·Yuping LiuTao Peng
Jan 16, 2019·Case Reports in Nephrology and Dialysis·Christine FirthLeslie F Thomas

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Methods Mentioned

BETA
ESR
biopsy
biopsies

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