PMID: 4967475May 24, 1968

Cross-link in fibrin polymerized by factor 13: epsilon-(gamma-glutamyl)lysine

J J PisanoM P Peyton


(epsilon)-((gamma)-Glutamyl)lysine has been isolated from enzymatic hydrolyzates of cross-linked human fibrin. This compound was not detected in "non-cross-linked" fibrin prepared with ethylenediaminetetraacetic acid, which inhibits factor XIII; intermediate amounts were observed when the fibrin was prepared with glycine ethyl ester, which inhibits factor XIII competitively. These and ancillary experiments furnish conclusive evidence that epsilon-(gamma-glutamyl)lysine cross-links form in human fibrin during polymerization catalyzed by factor XIII.


Jun 20, 1978·Annals of the New York Academy of Sciences·G M Fuller
Dec 1, 1992·Neurochemical Research·A CampisiA Vanella
Feb 1, 1990·International Journal of Peptide and Protein Research·R PortaS Metafora
Mar 1, 1989·European Journal of Biochemistry·S NuryA Mouranche
Dec 8, 1972·Annals of the New York Academy of Sciences·P A McKeeR L Hill
Mar 1, 1970·The British Journal of Nutrition·J Bjarnason, K J Carpenter
Apr 9, 1981·Nature·P J Gaffney
Jun 21, 2005·The Journal of Biological Chemistry·Judith A MackEdward V Maytin
Aug 29, 2009·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Pierre MorangePhilippe de Mazancourt
Jan 24, 2012·Anesthesia and Analgesia·Richard B Weiskopf
Jul 27, 2011·Journal of Molecular Neuroscience : MN·Lars DolgeWerner Baumgartner
Sep 3, 2013·Dermatology Research and Practice·Jill Henley, Jerry D Brewer
Jun 7, 2013·Biotechnology and Bioengineering·Jae-Hun LeeByung-Gee Kim
Jan 20, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Humphrey Petersen-JonesStephanie W Watts
Aug 10, 2018·Expert Review of Proteomics·Per HägglundMichael J Davies
Feb 5, 2019·Micromachines·Maria Pia SavocaElisabetta A M Verderio
Nov 1, 1987·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·H F UpchurchM D Maxwell
Mar 1, 1969·Journal of Biomedical Materials Research·H S Kingdon
Dec 8, 1972·Annals of the New York Academy of Sciences·J J PisanoJ S Finlayson
May 1, 1980·Journal of Clinical Pathology·F Rodeghiero, T Barbui
Jul 20, 2001·Annals of the New York Academy of Sciences·V W M van HinsberghP Koolwijk
Jul 20, 2001·Annals of the New York Academy of Sciences·L Lorand
Dec 1, 2009·Journal of Thrombosis and Haemostasis : JTH·V J Marder, V Novokhatny
Dec 2, 2011·Seminars in Immunopathology·Andrea DeDentOlaf Schneewind
Nov 8, 2012·Doklady. Biochemistry and Biophysics·M A RosenfeldM L Konstantinova
Feb 1, 1978·British Journal of Haematology·T BarbuiC M Umana
Dec 8, 1972·Annals of the New York Academy of Sciences·L Lorand
Aug 1, 1974·Angewandte Chemie·R S AsquithW J Sinclair
Dec 8, 1972·Annals of the New York Academy of Sciences·K Laki
Nov 1, 1976·Journal of the Science of Food and Agriculture·M S Otterburn, W J Sinclair
Jun 20, 1978·Annals of the New York Academy of Sciences·P J Birckbichler, M K Patterson
Mar 12, 1993·International Journal of Cancer. Journal International Du Cancer·S BeninatiM Cardinali
Jan 1, 1984·Molecular and Cellular Biochemistry·M Griffin, J Wilson
Sep 1, 1972·CRC Critical Reviews in Clinical Laboratory Sciences·M Stefanini
Dec 8, 1972·Annals of the New York Academy of Sciences·S I Chung
Feb 13, 2003·Journal of Neuropathology and Experimental Neurology·Magdalena O ZemaitaitisNancy A Muma
Aug 24, 1999·The Journal of Biological Chemistry·T S LaiC S Greenberg
Jan 13, 2001·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Y FurutaniS Hirose
Sep 12, 2006·Journal of Thrombosis and Haemostasis : JTH·E L KaijzelM P M de Maat
Aug 14, 2012·Biotechnology and Bioengineering·Jae-Hun LeeByung-Gee Kim
Jun 9, 2017·Haemophilia : the Official Journal of the World Federation of Hemophilia·Y AmriN E H Toumi
Sep 1, 1985·Journal of Cellular Physiology·G Korner, U Bachrach
Jan 1, 1975·International Journal of Peptide and Protein Research·J H Bradbury, D E Peters
Nov 1, 1992·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·P J RobinsonD S Harper
Feb 1, 1974·British Journal of Haematology·R D RosenbergL Lorand
May 15, 1980·International Journal of Cancer. Journal International Du Cancer·G de PetroS Barlati
Jan 27, 2005·Journal of Thrombosis and Haemostasis : JTH·M AnwarM Ayyub
Oct 22, 2014·Blood·Joanne L MitchellNicola J Mutch
Aug 21, 2018·Advanced Materials·Anna SorushanovaDimitrios I Zeugolis
Nov 23, 2019·Biochemical Society Transactions·Jessica L ChittyThomas R Cox
Sep 1, 1971·British Journal of Haematology·R P McDonaghF Duckert
Jan 1, 1974·Preparative Biochemistry·B A ChibberE T Mertz
Feb 1, 1980·Scandinavian Journal of Haematology·K M Rao, T F Newcomb
Jun 28, 2005·Journal of Thrombosis and Haemostasis : JTH·L Lorand
Dec 3, 2003·The Journal of Biological Chemistry·Bijan AhvaziFraydoon Rastinejad
Nov 21, 2014·Expert Opinion on Therapeutic Targets·Ana-Marija SulicKatri Lindfors
Feb 7, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Kyle B JohnsonStephanie W Watts
May 1, 1971·Australian and New Zealand Journal of Medicine·J W Hamer, B A Rae
Aug 1, 1973·CRC Critical Reviews in Biochemistry·E Triantaphyllopoulos, D C Triantaphyllopoulos

Related Concepts

Autoanalysis Procedure
Carbonic Acid Ions
Blood Coagulation
Blood Coagulation Factor
Ion-Exchange Chromatography Procedure
Physical Dialysis
Edetic Acid, Sodium Salt
Antithrombin I
Lysine Hydrochloride

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.