PMID: 18720556Aug 23, 2008Paper

Cross-linked and non-cross-linked collagen barrier membranes disintegrate following surgical exposure to the oral environment: a histological study in the cat

Clinical Oral Implants Research
H TalOfer Moses

Abstract

Early barrier membrane degradation may result in decreased bone formation in guided bone regeneration (GBR) procedures. The aim of this study was to evaluate the bio-degradation of cross-linked (CLM) and non-cross-linked (NCLM) collagen membranes experimentally exposed to the oral environment of study animals. In eight cats, 48 surgical procedures were performed, three along each side of the palate: 24 full-thickness soft tissue perforations were made and 24 full-thickness mini-flaps were raised. CLM or NCLM discs were placed either under the perforations and peripheral mucosa and left exposed (experimental) or covered by the flaps (controls). The four treatment modalities were equally distributed among the eight animals. Block sections were retrieved at 7 and 28 days post-operatively, providing histological specimens (6 each) at 7 and 28 days for each treatment modality. Histological observation revealed that CLM and NCLM remained intact in the control sites during the 28 days. At 7 and 28 days, CLM appeared interrupted in three and two experimental sites, respectively, and were undetected in the remaining sites. NCLM were interrupted in two sites each at 7 and 28 days, and were undetected in the other sites. There was no stat...Continue Reading

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Citations

May 29, 2012·Journal of Periodontology·Meizi EliezerOfer Moses
Jul 30, 2010·Clinical Oral Implants Research·Avigdor KlingerYuval Zubery
Jun 13, 2014·Journal of Tissue Engineering and Regenerative Medicine·Lindsay S Karfeld-SulzerFranz E Weber
Feb 28, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jung-Im ParkUi-Won Jung
Jul 12, 2013·International Journal of Dentistry·Gaia PellegriniGiulio Rasperini
May 18, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Marco C BottinoGregg M Janowski
Oct 25, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Hossein E JazayeriLobat Tayebi
Jul 11, 2009·American Journal of Physical Anthropology·Bonaventura Majolo, Richard McFarland
Apr 14, 2016·Maxillofacial Plastic and Reconstructive Surgery·Seong-Gon KimJeong Keun Lee
Jun 14, 2019·Journal of Periodontal Research·Meizi EliezerOfer Moses
Dec 11, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ankit J BavariyaJoel D Bumgardner
Aug 25, 2019·Journal of Clinical Periodontology·Hyun-Chang LimJung-Chul Park
Jan 23, 2020·Clinical Advances in Periodontics·Ahmed Gamil Ibraheem, Steven B Blanchard
Nov 5, 2014·Clinical Oral Implants Research·Joshua ChouMakoto Otsuka
Feb 16, 2018·Journal of Periodontal Research·E CalciolariN Donos
Feb 14, 2020·Materials·Luca SbricoliLivia Nastri
Jun 24, 2017·International Journal of Implant Dentistry·Mehmet A EskanHenry Greenwell
Apr 6, 2021·Bioactive Materials·Hyun Nyun WooChang H Lee
Jun 16, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kai ChenYubo Fan
Aug 20, 2021·Tissue Engineering. Part B, Reviews·Brittany AllenDeborah S F Kacmarynski

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