Cross-participant prediction of vigilance stages through the combined use of wPLI and wSMI EEG functional connectivity metrics.

Sleep
Laura S ImperatoriGiulio Bernardi

Abstract

Functional connectivity (FC) metrics describe brain inter-regional interactions and may complement information provided by common power-based analyses. Here, we investigated whether the FC-metrics weighted Phase Lag Index (wPLI) and weighted Symbolic Mutual Information (wSMI) may unveil functional differences across four stages of vigilance-wakefulness (W), NREM-N2, NREM-N3, and REM sleep-with respect to each other and to power-based features. Moreover, we explored their possible contribution in identifying differences between stages characterized by distinct levels of consciousness (REM+W vs. N2+N3) or sensory disconnection (REM vs. W). Overnight sleep and resting-state wakefulness recordings from 24 healthy participants (27 ± 6 years, 13F) were analyzed to extract power and FC-based features in six classical frequency bands. Cross-validated linear discriminant analyses (LDA) were applied to investigate the ability of extracted features to discriminate (1) the four vigilance stages, (2) W+REM vs. N2+N3, and (3) W vs. REM. For the four-way vigilance stages classification, combining features based on power and both connectivity metrics significantly increased accuracy relative to considering only power, wPLI, or wSMI features. D...Continue Reading

References

Jan 18, 2003·Sleep Medicine Reviews·Robert D. Ogilvie
Oct 8, 2003·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Jorge IriarteJulio Artieda
Aug 6, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marcello MassiminiGiulio Tononi
Oct 1, 2005·Science·Marcello MassiminiGiulio Tononi
Dec 17, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jürgen Kayser, Craig E Tenke
Nov 29, 2007·Sleep·Christian BerthomierMarie-Pia d'Ortho
Jul 2, 2008·Annals of the New York Academy of Sciences·Giulio Tononi, Marcello Massimini
May 23, 2009·Science·Sydney S CashIstván Ulbert
Jan 19, 2010·Trends in Cognitive Sciences·Yuval Nir, Giulio Tononi
Jan 22, 2011·Computational Intelligence and Neuroscience·Robert OostenveldJan-Mathijs Schoffelen
Dec 14, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Thomas AndrillonItzhak Fried
Oct 30, 2012·Computers in Biology and Medicine·B Koley, D Dey
Aug 24, 2013·Frontiers in Psychology·Francesca SiclariGiulio Tononi
Oct 1, 2013·Current Biology : CB·Jean-Rémi KingStanislas Dehaene
Jan 10, 2014·Clinical EEG and Neuroscience·Simone SarassoMarcello Massimini
Jun 13, 2014·Brain : a Journal of Neurology·Jacobo Diego SittLionel Naccache
Jul 30, 2014·Frontiers in Systems Neuroscience·Stefanie Blain-MoraesGeorge A Mashour
Oct 21, 2014·PLoS Computational Biology·Srivas ChennuTristan A Bekinschtein
Nov 26, 2015·Sleep Medicine Reviews·Péter Halász
Jan 26, 2016·Current Biology : CB·Chadd M FunkGiulio Tononi
Apr 11, 2017·Nature Neuroscience·Francesca SiclariGiulio Tononi
Jul 27, 2017·Human Brain Mapping·Fabrizio VecchioPaolo Maria Rossini
Dec 3, 2017·Scientific Reports·Minji LeeSeong-Whan Lee
Sep 12, 2018·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Francesca SiclariGiulio Tononi
Oct 5, 2018·Brain : a Journal of Neurology·Denis A EngemannJacobo D Sitt
Nov 11, 2018·Scientific Reports·Matthieu DarracqRobert D Sanders
Feb 10, 2019·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Giulio BernardiFrancesca Siclari
Apr 4, 2019·Journal of Neurophysiology·Giulio BernardiFrancesca Siclari

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Citations

Jun 25, 2021·Brain Communications·Giulio BernardiMichele Bellesi
Oct 13, 2021·Journal of Neuroscience Research·Jiakai LianYuxi Luo

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