PMID: 9534913Apr 16, 1998Paper

Cross-reactivity between terrestrial snails (Helix species) and house-dust mite (Dermatophagoides pteronyssinus). II. In vitro study

Allergy
L GuillouxG Ville

Abstract

Epidemiologic and in vitro data have shown that the association of house-dust mite (HDM) allergy and snail allergy in the same patients was due to cross-reactivity between HDM and snail allergenic components. However, the cross-reacting allergen(s) have not yet been identified. In vitro reactivity of seven patients' sera to the various extracts and hemolymph of four different Helix snail species was analyzed by IgE detection and immunodots and Western blots. Cross-reactivity between snails and Dermatophagoides pteronyssinus was assessed by immunodot and ELISA inhibition in two patients. Heterologous inhibition of the snail immunodot and ELISA was observed in one serum. Western blotting showed a specific binding on all four snail species extracts; molecular weights of snail allergens ranged from < 21 to 200 kDa. Marked individual differences were observed in the seven sera under study; most sera demonstrated IgE recognition of multiple bands, illustrating that no single allergen is responsible for cross-reactivity between snail and mite. These results confirm that cross-reactivity exists between snails of the Helix genus and HDM. This cross-reactivity, involving more than a single allergen, may be of clinical significance in ato...Continue Reading

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Citations

Jul 10, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·P GaigC Richart
Dec 14, 2004·International Archives of Allergy and Immunology·Luís Miguel Lourenço MartinsFilipe Fernando da Cruz Inácio
Jan 8, 2016·Allergy, Asthma & Immunology Research·Lydia WongBee Wah Lee
Jul 14, 2010·The Journal of Allergy and Clinical Immunology·Lynette Pei-Chi ShekBee Wah Lee
Apr 2, 2008·Regulatory Toxicology and Pharmacology : RTP·B BjörksténR Ward
Mar 8, 2003·Allergy·J F Crespo, J Rodriguez
Dec 16, 2006·The Korean Journal of Parasitology·Sung-Weon Cho, Haneul Nari Lee
Dec 28, 2016·Allergy·M A FaberD G Ebo
Jun 28, 2017·Molecular Nutrition & Food Research·José Carlos RibeiroJoão Fonseca
Jul 12, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Jose F CantilloBarbara Bohle
Jul 31, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Yvonne Schmidt-HieltjesJanneke Ruinemans-Koerts

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