Cross-regulatory interactions among pair-rule genes in Drosophila

Science
K HardingM Levine

Abstract

The pair-rule genes of Drosophila are required for the subdivision of the developing embryo into a repeating series of homologous body segments. One of the pair-rule genes, even-skipped (eve), appears to be particularly important for the overall segmentation pattern since eve- embryos lack all segmental subdivisions in the middle body region. On the basis of homeo box cross-homology we have isolated a gene, S72, which probably corresponds to eve. In embryo tissue sections S72 transcripts show a periodic distribution pattern. The eve- phenotype appears to involve altered patterns of fushi tarazu and engrailed expression. These and other findings suggest that pair-rule gene expression might involve hierarchical cross-regulatory interactions.

References

Jun 1, 1976·Developmental Biology·P A Lawrence, G Morata
Jan 1, 1985·Cold Spring Harbor Symposia on Quantitative Biology·C Nüsslein-VolhardG Jürgens
Jan 1, 1985·Cold Spring Harbor Symposia on Quantitative Biology·M LevineH Radomska
Jan 10, 1985·Nature·E Sánchez-HerreroG Morata
Nov 1, 1985·Cell·F KarchE B Lewis
Oct 30, 1980·Nature·C Nüsslein-Volhard, E Wieschaus
Sep 1, 1984·Wilhelm Roux's Archives of Developmental Biology·C Nüsslein-VolhardH Kluding

❮ Previous
Next ❯

Citations

Aug 26, 1998·Developmental Genetics·J ReinitzD H Sharp
Aug 26, 1998·Developmental Genetics·P A Lawrence, L Pick
Sep 27, 2002·Genesis : the Journal of Genetics and Development·Yashoda SharmaDaniel F Eberl
Nov 17, 2010·Cellular and Molecular Life Sciences : CMLS·Vivek S Chopra
Nov 1, 1987·Developmental Biology·A FainsodF H Ruddle
Jul 28, 1989·Biochimica Et Biophysica Acta·M P ScottG W Hartzell
Dec 16, 1992·Biochimica Et Biophysica Acta·D Read, J L Manley
Sep 1, 1993·Mechanisms of Development·M Klingler, J P Gergen
Sep 6, 2003·Journal of Theoretical Biology·Lucas Sánchez, Denis Thieffry
Jul 3, 2013·Nature Methods·Justin Crocker, David L Stern
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·C RussoM Tabaton
Dec 1, 2001·Annual Review of Entomology·Gregory K Davis, Nipam H Patel
Jan 8, 2011·BMC Evolutionary Biology·Carlos Espinosa-SotoAndreas Wagner
Mar 1, 2011·EvoDevo·Ralf JanssenWim Gm Damen
Mar 8, 2014·PLoS Computational Biology·Md Abul Hassan Samee, Saurabh Sinha
Aug 1, 1987·American Journal of Obstetrics and Gynecology·P M IannacconeC S Connelly
Mar 5, 2016·Integrative Biology : Quantitative Biosciences From Nano to Macro·Ben J VincentAngela H DePace
Sep 23, 1988·Cell·C DesplanP H O'Farrell
Oct 1, 1988·Journal of Neuroscience Research·C A GardnerK F Barald

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.