Cross-Resistance: A Consequence of Bi-partite Host-Parasite Coevolution

Insects
Tilottama BiswasCharlotte Rafaluk-Mohr

Abstract

Host-parasite coevolution can influence interactions of the host and parasite with the wider ecological community. One way that this may manifest is in cross-resistance towards other parasites, which has been observed to occur in some host-parasite evolution experiments. In this paper, we test for cross-resistance towardsBacillus thuringiensisandPseudomonasentomophilain the red flour beetleTriboliumcastaneum, which was previously allowed to coevolve with the generalist entomopathogenic fungusBeauveriabassiana. We combine survival and gene expression assays upon infection to test for cross-resistance and underlying mechanisms. We show that larvae ofT.castaneumthat evolved withB.bassianaunder coevolutionary conditions were positively cross-resistant to the bacteriumB. thuringiensis,but notP.entomophila. Positive cross-resistance was mirrored at the gene expression level with markers that were representative of the oral route of infection being upregulated uponB.bassianaexposure. We find that positive cross-resistance towardsB. thuringiensisevolved inT.castaneumas a consequence of its coevolutionary interactions withB.bassiana. This cross-resistance appears to be a consequence of resistance to oral toxicity. The fact that coevolut...Continue Reading

References

Aug 6, 2004·Proceedings. Biological Sciences·Jacobus C de RoodeAndrew F Read
Aug 4, 2005·Proceedings of the National Academy of Sciences of the United States of America·Yasuyuki ArakaneKarl J Kramer
Dec 17, 2005·Science·Claire L ScarboroughH C J Godfray
Jan 3, 2007·Toxicon : Official Journal of the International Society on Toxinology·Alejandra BravoMario Soberón
Nov 6, 2007·Developmental and Comparative Immunology·Boran AltincicekAndreas Vilcinskas
Nov 16, 2007·Nature·Ellen DecaesteckerLuc De Meester
Feb 28, 2008·Heredity·A R Kraaijeveld, H C J Godfray
Aug 19, 2008·The American Naturalist·Marlene Zuk, Andrew M Stoehr
Sep 18, 2008·Proceedings. Biological Sciences·Olivia RothJoachim Kurtz
Mar 10, 2009·Insect Biochemistry and Molecular Biology·Yasuyuki ArakaneRichard W Beeman
Oct 21, 2009·The Journal of Animal Ecology·Olivia RothJoachim Kurtz
Apr 7, 2010·Proceedings of the National Academy of Sciences of the United States of America·Rebecca D SchulteHinrich Schulenburg
Aug 6, 2010·Proceedings. Biological Sciences·Camillo BérénosPaul Schmid-Hempel
Dec 16, 2011·Proceedings. Biological Sciences·Britt KoskellaJohn N Thompson
Feb 15, 2012·BMC Evolutionary Biology·Niels A G KerstesK Mathias Wegner
Apr 24, 2012·PloS One·Anabelle Reber, Michel Chapuisat
Jan 29, 2013·Applied and Environmental Microbiology·Benjamin J ParkerNicole M Gerardo
Mar 26, 2013·Trends in Ecology & Evolution·Michael A Brockhurst, Britt Koskella
Apr 6, 2013·PloS One·Ivan M DubovskiyTariq M Butt
Jun 6, 2013·PloS One·Barbara MilutinovićJoachim Kurtz
Aug 27, 2013·PloS One·Mikhail V MatzJames G Scott
Oct 3, 2013·PLoS Pathogens·Nelson E MartinsÉlio Sucena
Apr 9, 2014·Proceedings of the National Academy of Sciences of the United States of America·Nelson E MartinsSara Magalhães
Aug 1, 2015·Journal of Invertebrate Pathology·L A LaceyM S Goettel
Oct 27, 2015·Evolution; International Journal of Organic Evolution·Vítor G FariaSara Magalhães
Feb 5, 2016·Proceedings. Biological Sciences·Nina Hafer, Manfred Milinski
May 20, 2016·Proceedings. Biological Sciences·Denon Start, Benjamin Gilbert
Oct 31, 2016·Trends in Parasitology·Alex BettsKayla C King

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
spore collection
electrophoresis
PCR

Software Mentioned

survival
Oligo Explorer
MCMC
R
StepOne
qpcr R package

Related Concepts

Related Feeds

Babesiosis

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.