Cross-shift changes in FEV1 in relation to wood dust exposure: the implications of different exposure assessment methods

Occupational and Environmental Medicine
Vivi SchlünssenHans Kromhout

Abstract

Exposure-response analyses in occupational studies rely on the ability to distinguish workers with regard to exposures of interest. To evaluate different estimates of current average exposure in an exposure-response analysis on dust exposure and cross-shift decline in FEV1 among woodworkers. Personal dust samples (n = 2181) as well as data on lung function parameters were available for 1560 woodworkers from 54 furniture industries. The exposure to wood dust for each worker was calculated in eight different ways using individual measurements, group based exposure estimates, a weighted estimate of individual and group based exposure estimates, and predicted values from mixed models. Exposure-response relations on cross-shift changes in FEV1 and exposure estimates were explored. A positive exposure-response relation between average dust exposure and cross-shift FEV1 was shown for non-smokers only and appeared to be most pronounced among pine workers. In general, the highest slope and standard error (SE) was revealed for grouping by a combination of task and factory size, the lowest slope and SE was revealed for estimates based on individual measurements, with the weighted estimate and the predicted values in between. Grouping by q...Continue Reading

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Citations

Apr 7, 2011·The Annals of Occupational Hygiene·Richard L NeitzelNoah S Seixas
Sep 28, 2012·Occupational and Environmental Medicine·Gitte Højbjerg JacobsenTorben Sigsgaard
Oct 21, 2015·Occupational Medicine·R E WiggansC M Barber
Mar 10, 2017·Upsala Journal of Medical Sciences·Håkan LöfstedtAnna Rask-Andersen
Mar 30, 2017·Annals of Work Exposures and Health·Jeroen DouwesJames D McGlothlin
Aug 31, 2018·Annals of Work Exposures and Health·Anneli C S BolundVivi Schlünssen

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