Cross-validation, predictive validity, and time course of the Benzodiazepine Dependence Self-Report Questionnaire in a benzodiazepine discontinuation trial

Comprehensive Psychiatry
Richard C Oude VoshaarFrans Zitman

Abstract

The Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ) measures the severity of benzodiazepine (BZ) dependence on four domains: awareness of problematic use, preoccupation with the availability of BZ, lack of compliance with the therapeutic regimen, and withdrawal. Although promising results of the Bendep-SRQ have been obtained in cross-sectional studies, no attention has been paid to its clinical relevance during BZ withdrawal, i.e., predictive validity and time course. We performed cross-validation and evaluated the predictive validity and time course on 180 long-term BZ users who were taking part in a general practice BZ discontinuation trial. Three of the four domains had good scalability. Some concerns arose about the preoccupation scale, which emphasizes the need for cross-validation in clinically relevant populations. All scales showed excellent reliability (subject discriminability, item discriminability), while construct and discriminant validity were adequate. All four scales contributed significantly to the prediction of whether complete abstinence would be achieved directly after taking part in the discontinuation program. This prediction was independent of the other prognostic variables, except for th...Continue Reading

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Citations

May 1, 2012·Journal of Affective Disorders·Ozgür AtlıTunç Alkın
Jun 4, 2010·Journal of Clinical Psychopharmacology·Leonie MantheyFrans G Zitman
Sep 4, 2008·International Journal of Methods in Psychiatric Research·Brenda W J H PenninxUNKNOWN NESDA Research Consortium
Aug 22, 2013·British Journal of Clinical Pharmacology·Leonie MantheyFrans G Zitman
Jan 1, 2010·Indian Journal of Psychiatry·Pratima MurthyVivek Benegal
Jan 1, 2010·Indian Journal of Psychiatry·Ashish SrivastavaP S V N Sharma
Mar 25, 2016·Indian Journal of Psychological Medicine·Shalini Singh, Yatan Pal Singh Balhara
Sep 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Richard C Oude VoshaarFrans G Zitman
Jun 25, 2015·The Cochrane Database of Systematic Reviews·Catherine D DarkerErica Donnelly-Swift
Jul 15, 2006·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Richard C Oude VoshaarFrans G Zitman
Dec 3, 2020·Trends in psychiatry and psychotherapy·Daniela F CuradoAna Regina Noto

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