Crosslinked polymeric ionic liquids as solid-phase microextraction sorbent coatings for high performance liquid chromatography

Journal of Chromatography. a
Honglian YuJared L Anderson

Abstract

Neat crosslinked polymeric ionic liquid (PIL) sorbent coatings for solid-phase microextraction (SPME) compatible with high-performance liquid chromatography (HPLC) are reported for the first time. Six structurally different PILs were crosslinked to nitinol supports and applied for the determination of select pharmaceutical drugs, phenolics, and insecticides. Sampling conditions including sample solution pH, extraction time, desorption solvent, desorption time, and desorption solvent volume were optimized using design of experiment (DOE). The developed PIL sorbent coatings were stable when performing extractions under acidic pH and remained intact in various organic desorption solvents (i.e., methanol, acetonitrile, acetone). The PIL-based sorbent coating polymerized from the IL monomer 1-vinyl-3-(10-hydroxydecyl) imidazolium chloride [VC10OHIM][Cl] and IL crosslinker 1,12-di(3-vinylbenzylimidazolium) dodecane dichloride [(VBIM)2C12] 2[Cl] exhibited superior extraction performance compared to the other studied PILs. The extraction efficiency of pharmaceutical drugs and phenolics increased when the film thickness of the PIL-based sorbent coating was increased while many insecticides were largely unaffected. Satisfactory analytica...Continue Reading

References

Oct 1, 1996·Journal of Pharmaceutical Sciences·C Bustamante, P Bustamante
Sep 3, 2004·Journal of Controlled Release : Official Journal of the Controlled Release Society·Taravat GhafourianAli Nokhodchi
Dec 30, 2009·Analytical Chemistry·Qichao ZhaoJared L Anderson
Jan 24, 2012·Journal of Chromatography. a·Juanjuan FengShengxiang Jiang
Nov 12, 2013·Analytical Chemistry·Tien D HoJared L Anderson
Dec 10, 2015·Analytical Chemistry·German A Gomez-RiosJanusz Pawliszyn

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Citations

Sep 20, 2017·Journal of Separation Science·Kevin D ClarkJared L Anderson
Dec 26, 2018·Critical Reviews in Analytical Chemistry·Muhammad SajidJustyna Płotka-Wasylka
Apr 22, 2019·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Sângela Nascimento do CarmoEduardo Carasek
Jan 1, 2021·Talanta·Herbert Musarurwa, Nikita Tawanda Tavengwa
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ahmad UmarSotirios Baskoutas

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