Crucial differences in the hydrolytic degradation between industrial polylactide and laboratory-scale poly(L-lactide).

ACS Applied Materials & Interfaces
Anders HoglundAnn-Christine Albertsson

Abstract

The rate of degradation of large-scale synthesized polylactide (PLA) of industrial origin was compared with that of laboratory-scale synthesized poly(L-lactide) (PLLA) of similar molar mass. The structural discrepancy between the two material types resulted in a significant difference in degradation rate. Although the hydrolysis of industrial PLA was substantially faster than that of PLLA, the PLA material became less brittle and fragmented to a lesser extent during degradation. In addition, a comprehensive picture of the degradation of industrial PLA was obtained by subjecting different PLA materials to hydrolytic degradation at various temperatures and pH's for up to 182 days. The surrounding environment had no effect on the degradation rate at physiological temperature, but the degradation was faster in water than in a phosphate buffer after prolonged degradation at temperatures above the T(g). The degree of crystallinity had a greater influence than the degradation environment on the rate of hydrolysis. For a future use of polylactide in applications where bulk plastics are generally used today, for example plastic packages, the appropriate PLA grade must be chosen based on the conditions prevailing in the degradation envir...Continue Reading

References

Nov 11, 2003·Biomacromolecules·Ann-Christine Albertsson, Indra K Varma
Nov 10, 2004·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·N A WeirG R Dickson
Sep 13, 2005·Biomacromolecules·Karin OdeliusAnn-Christine Albertsson
Jun 21, 2007·Biomacromolecules·Suping LyuDarrel Untereker
Dec 30, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Anders HöglundAnn-Christine Albertsson
Mar 6, 2010·Biomacromolecules·Sofia Regnell AnderssonAnn-Christine Albertsson
Apr 2, 2010·ACS Applied Materials & Interfaces·Kwanho ChangMarc A Hillmyer
Nov 18, 2010·Biomacromolecules·Sofia Regnell AnderssonAnn-Christine Albertsson
Aug 10, 2011·ACS Applied Materials & Interfaces·Megan L RobertsonMarc A Hillmyer
Nov 19, 2011·Macromolecular Bioscience·Anders HöglundAnn-Christine Albertsson

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Citations

Mar 9, 2013·Journal of Materials Science. Materials in Medicine·Mikko Huttunen
Jan 1, 2015·International Journal of Molecular Sciences·Joanna RydzDarinka Christova
Nov 28, 2013·Biomacromolecules·Veluska AriasAnn-Christine Albertsson
May 12, 2015·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Dorien M van der EngTim Schepers
Oct 14, 2018·Materials·Iozzino ValentinaPantani Roberto
Aug 12, 2016·ACS Applied Materials & Interfaces·Virginia PensabeneWilliam H Hofmeister

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