PMID: 16511955Mar 4, 2006Paper

Cryoplasty for the treatment of femoropopliteal arterial disease: extended follow-up results

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
J R LairdJames D Joye

Abstract

To report the findings from a multicenter study of patients treated with cryoplasty who were then followed for an average of > 2 years post-treatment. Extended clinical follow-up was obtained for 70 patients (45 men; mean age 70.5 +/- 8.8 years) who originally received cryoplasty therapy to treat symptoms of intermittent claudication as part of a multicenter investigational device exemption (IDE) study. For all subjects, cryoplasty was used to treat stenoses or occlusions < or = 10 cm in the femoropopliteal arteries. The original IDE study protocol enrolled 102 patients with a primary endpoint of target lesion patency at 9 months post-treatment. This collection of additional longer term follow-up data was initiated 2.5 years after the onset of study enrollment. Extended clinical follow-up ranged from 11 to 41 months (mean 31). The clinical patency rate (freedom from target lesion revascularization) calculated by the Kaplan-Meier method was 83.2% after the original follow-up period of 300 days. After > 3 years (1253 days), the clinical patency rate was well maintained at 75.0%. Long-term data indicate that cryoplasty is a durable therapy, with relatively low long-term restenosis rates compared to other endovascular treatment app...Continue Reading

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Citations

Mar 1, 2008·Seminars in Interventional Radiology·Martin G Radvany, R Stefan Kiesz
Jul 25, 2009·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Alan B Lumsden, Tony S Das
Jul 25, 2009·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Sean P Lyden, H Bob Smouse
Jul 25, 2009·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Alan B LumsdenEric K Peden

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