Cryopreserved amniotic membrane for modulation of periodontal soft tissue healing: a pilot study

Journal of Periodontology
Ines VelezMaria Hernandez

Abstract

The purpose of this randomized study is to evaluate cryopreserved amniotic membrane (CAM) for helping cicatrization and wound healing after dental implant surgery. Epithelialization, pain, infection, inflammation, and scarring were studied. CAM was placed in surgical wounds related to implant surgery. The extent of healing was evaluated by a masked investigator for lesion size, epithelialization, pain, infection, inflammation, and scarring. A clinical evaluation occurred at baseline, 72 and 144 hours, 2 weeks, and 1, 1.5, and 3 months. The results were compared to conventionally managed, similar lesions that were treated the same day in the same patient allowing each patient to serve as their own control. This prospective randomized study showed statistically significant differences between experimental and control groups regarding cicatrization, wound healing, and pain. The effects of the membrane were statistically significant during the first 3 weeks of the study, and thereafter, the effects of the membrane for the two groups were equivalent. CAM was effective in helping cicatrization and wound healing. CAM supported the growth of the epithelium and, thus, facilitated migration and reinforced adhesion. It also decreased the ...Continue Reading

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Citations

Dec 18, 2012·Oral and Maxillofacial Surgery·Marco Rainer KestingNils Hagen Rohleder
Dec 20, 2013·Cell and Tissue Banking·Tina CirmanMateja Erdani Kreft
Sep 6, 2014·Contemporary Clinical Dentistry·Rucha ShahD S Mehta
May 2, 2012·Journal of Clinical Periodontology·Colman McGrathNiklaus Lang
Sep 24, 2015·Journal of Indian Society of Periodontology·Anamika Sharma, Komal Yadav
Nov 27, 2015·Journal of Dental Research·L LarssonW V Giannobile
Sep 3, 2019·Journal of Periodontology·Lorenzo TavelliWilliam V Giannobile
Apr 3, 2018·Journal of Investigative and Clinical Dentistry·Sarah Grace GeorgeJeethu John Jerry

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