Cryopreserved Ultra-Thick Human Amniotic Membrane for Conjunctival Surface Reconstruction After Excision of Conjunctival Tumors

Cornea
Thais S Tanaka, Hakan Demirci

Abstract

Cryopreserved ultra-thick human amniotic membrane (AM) is used for glaucoma surgery. We evaluated the use of cryopreserved ultra-thick human AM for conjunctival surface reconstruction after excision of a conjunctival tumor. We retrospectively reviewed the medical records of 28 patients who underwent conjunctival surface reconstruction with cryopreserved ultra-thick human AM after excision of the tumor. The AM was secured to the surrounding conjunctiva and underlying sclera with interrupted 8-0 Vicryl sutures. Clinical data regarding demographics, diagnosis, size and location of conjunctival tumors, patient outcome, and complications were gathered. Of 28 patients, 6 (21.4%) had malignant melanoma, 4 (14.3%) had squamous cell carcinoma, 6 (21.4%) had conjunctival intraepithelial neoplasia, 1 (3.6%) had sebaceous carcinoma, 1 (3.6%) had mucoepidermoid carcinoma, 1 (3.6%) had conjunctival intraepithelial dysplasia, 5 (17.9%) had pterygium, 2 (7.1%) had compound nevus, 1 (3.6%) had a large epithelial inclusion cyst, and 1 (3.6%) patient had a granuloma. The mean area of graft size was 156 ± 120 mm2. Postoperatively, the graft was well tolerated with no failure, discomfort, or dehiscence. During the 17-month mean follow-up, symblepha...Continue Reading

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Citations

Jun 21, 2016·Survey of Ophthalmology·Gargi K VoraPrithvi Mruthyunjaya
Nov 9, 2018·Ophthalmic Plastic and Reconstructive Surgery·Dane H Slentz, Christine C Nelson
Nov 27, 2019·Ophthalmic Plastic and Reconstructive Surgery·Dane H SlentzChristine C Nelson
Jun 8, 2017·International Ophthalmology Clinics·Afshan A NanjiCarol L Karp
Jul 1, 2017·Journal of Ophthalmology·Hua-Tao XieMing-Chang Zhang
May 31, 2019·Journal of Biochemistry·Jian PanZipei Jiang

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