PMID: 16518265Mar 7, 2006Paper

Cryptococcal meningo-encephalitis in an apparently immunocompetent patient

Revue neurologique
K BretaudeauF Pico

Abstract

Cryptococcal meningo-encephalitis is a rare disease occurring more frequently in immunocompromised hosts. We report the case of an apparently immunocompetent patient who developed a recurrent neurological deficit with lymphocytic meningitis. The time from the first symptoms to diagnosis was 8 months. We noted mild CD4+ lymphocytopenia (500 cells/mm3) without HIV infection. CD4+ lymphocytes were not reactive for a panel of antigens. This case illustrates the usefulness of cerebrospinal fluid Cryptococcus Neoformans antigen test in patients with an unexplained neurological syndrome with a lymphocytic meningitis together with quantification of circulating lymphocytes clusters and analyse of their function in opportunistic infections.

Citations

Oct 30, 2008·Bulletin de la Société de pathologie exotique·M NdiayeI P Ndiaye
Mar 22, 2013·QJM : Monthly Journal of the Association of Physicians·C BernardUNKNOWN French Cryptococcosis Study Group
Jan 2, 2020·Clinical Case Reports·Jean-Baptiste BarbryOlivier Balland
Nov 17, 2020·Frontiers in Molecular Biosciences·Sandeep VellankiSoo Chan Lee

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