Cryptococcosis in Colombia: Compilation and Analysis of Data from Laboratory-Based Surveillance

Journal of Fungi
Patricia EscandónElizabeth Castañeda

Abstract

The passive and voluntary surveillance of cryptococcosis in Colombia since 1997 has seen an increasing participating rate, revealing its importance to both in immunosuppressed and immunocompetent people. The present work details the national data gathered in 1997-2016, through a retrospective analysis of the information collected in the survey. From a total of 1974 cases reported, an overall incidence of 0.23 cases per 100,000 people was found. This incidence rose to 1.1 cases per 1000 people in the Acquired Immunodeficiency Syndrome (AIDS) population. Cryptococcosis was most common in male young adults (26-40 years), with a male:female ratio of 3.9:1 in the general population and 5.4:1 in Human Immunodeficiency Virus (HIV) patients. Culture was the most common form of diagnosis in 96.3% of cases, recoveringC. neoformansspecies in 87.5% andC. gattiiin 3.1% of samples. VNI was the most prevalent (96.1%) molecular type, while VGII predominated inC. gattiiisolates (54.3%). Early mortality was reported as the outcome in 47.5% of patients. Cryptococcosis remains an important opportunistic disease in Colombia and is gaining status as a primary pathogen in apparently immunocompetent patients. Our findings show the importance of includ...Continue Reading

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Citations

May 1, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·María Clara NogueraElizabeth Castañeda
Apr 20, 2018·Journal of Fungi·Tiffany E GuessErin E McClelland
Sep 24, 2020·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Markos NegashFitsumbrhan Tajebe
Apr 18, 2019·Journal of Fungi·Carolina FiracativePatricia Escandón
Jun 3, 2021·Journal of Fungi·Briggith-Nathalia Serna-EspinosaZilpa Adriana Sánchez-Quitian

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