PMID: 11068329Nov 9, 2000

Cryptorchidism: fowler-stephens procedure or autotransplantation-a new experimental model

H SperlingH Rübben


To investigate the effect of different operative procedures on testicular development in cryptorchidism. One hundred ten postpubertal Wistar-WU rats were divided into four groups. Group 1 (35 rats) underwent microsurgical autotransplantation of the right testis with end-to-end anastomosis of the testicular vessels. Group 2 (35 rats) underwent the Fowler-Stephens maneuver with intra-abdominal fixation of the testis. To determine the influence of temperature on testicular development, group 3 (35 rats) underwent the Fowler-Stephens maneuver with scrotal replacement of the testis. Group 4 (5 rats) was a control group without operative treatment. To assess the early and late changes of testicular ischemia and reperfusion, groups 1 to 3 were divided into seven subgroups (5 rats each) with defined postoperative intervals (0.5 hour, 2 hours, 4 hours, 8 hours, 16 hours, 14 days, and 60 days). Testicular development, sperm density, pH value, tissue lactate concentration, and tubular diameter were the parameters used to determine success or failure. After autotransplantation, testicular development exhibited an atrophy rate of less than 50% and a significant decrease in groups 2 and 3 after 60 days. The sperm density was significantly di...Continue Reading


Sep 1, 1992·Urology·I Atlas, N Stone
Mar 1, 1971·Transplantation Proceedings·S LeeM J Orloff
Aug 1, 1959·The Australian and New Zealand Journal of Surgery·R FOWLER, F D STEPHENS
Dec 1, 1964·Archives of Disease in Childhood·C G SCORER


Jul 11, 2007·Der Urologe. Ausg. A·H SperlingH Rübben
Jul 11, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Hui ZhengYong-Yi Wang
May 18, 2016·Journal of Pediatric Surgery·Asudan Tugce Bozkurter CilEnder Ariturk
May 26, 2010·Acta Cirúrgica Brasileira·Saulo Rodrigues JúniorLázaro Bruno Borges Silva
Feb 3, 2006·Scandinavian Journal of Urology and Nephrology·Omer YilmazCan Taneli

Related Concepts

Anastomosis, Surgical
Unilateral Cryptorchidism
Hydrogen-Ion Concentration
Finding of Sperm Number
Rats, Wistar

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