Crystal identification in positron emission tomography using nonrigid registration to a Fourier-based template.

Physics in Medicine and Biology
Abhijit J ChaudhariRamsey D Badawi

Abstract

Modern positron emission tomography (PET) detectors are typically made from 2D modular arrays of scintillation crystals. Their characteristic flood field response (or flood histogram) must be segmented in order to correctly determine the crystal of annihilation photon interaction in the system. Crystal identification information thus generated is also needed for accurate system modeling as well as for detailed detector characterization and performance studies. In this paper, we present a semi-automatic general purpose template-guided scheme for the segmentation of flood histograms. We first generate a template image that exploits the spatial frequency information in the given flood histogram using Fourier-space analysis. This template image is a lower order approximation of the flood histogram, and can be segmented with horizontal and vertical lines drawn midway between adjacent peaks in the histogram. The template is then registered to the given flood histogram by a diffeomorphic polynomial-based warping scheme that is capable of iteratively minimizing intensity differences. The displacement field thus calculated is applied to the segmentation of the template resulting in a segmentation of the given flood histogram. We evaluat...Continue Reading

References

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Citations

Jun 18, 2009·Physics in Medicine and Biology·Yibao WuRamsey D Badawi
Aug 13, 2009·Physics in Medicine and Biology·Yibao WuSimon R Cherry
May 15, 2012·Physics in Medicine and Biology·Felipe GodinezRamsey D Badawi
Dec 5, 2014·IEEE Transactions on Nuclear Science·Jeffrey P SchmallSimon R Cherry
Jun 16, 2009·IEEE Transactions on Nuclear Science·Yibao WuSimon R Cherry
Sep 24, 2016·Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment·Han ShiQiyu Peng
Mar 7, 2012·Physics in Medicine and Biology·Joyita DuttaRichard M Leahy
Nov 23, 2012·Physics in Medicine and Biology·Jeffrey P SchmallSimon R Cherry

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