Crystal structure of bacterial inorganic polyphosphate/ATP-glucomannokinase. Insights into kinase evolution

The Journal of Biological Chemistry
Takako MukaiKousaku Murata

Abstract

Inorganic polyphosphate (poly(P)) is a biological high energy compound presumed to be an ancient energy carrier preceding ATP. Several poly(P)-dependent kinases that use poly(P) as a phosphoryl donor are known to function in bacteria, but crystal structures of these kinases have not been solved. Here we present the crystal structure of bacterial poly(P)/ATP-glucomannokinase, belonging to Gram-positive bacterial glucokinase, complexed with 1 glucose molecule and 2 phosphate molecules at 1.8 A resolution, being the first among poly(P)-dependent kinases and bacterial glucokinases. The poly(P)/ATP-glucomannokinase structure enabled us to understand the structural relationship of bacterial glucokinase to eucaryotic hexokinase and ADP-glucokinase, which has remained a matter of debate. These comparisons also enabled us to propose putative binding sites for phosphoryl groups for ATP and especially for poly(P) and to obtain insights into the evolution of kinase, particularly from primordial poly(P)-specific to ubiquitous ATP-specific proteins.

References

Apr 27, 1979·Science·C M AndersonT A Steitz
Aug 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·P BorkA Valencia
Jan 1, 1985·Archives of Biochemistry and Biophysics·P G Polakis, J E Wilson
Jan 1, 1985·Methods in Enzymology·B C Wang
Jan 1, 1968·Advances in Protein Chemistry·G N Ramachandran, V Sasisekharan
May 23, 1996·Nature·R W HooftE E Abola
Feb 14, 1998·The Journal of Biological Chemistry·C ZengH J Fromm
Apr 16, 1998·Biochimica Et Biophysica Acta·M L CárdenasT Ureta
Jul 17, 1998·Nature Structural Biology·A M MulichakR M Garavito
Oct 3, 1998·Acta Crystallographica. Section D, Biological Crystallography·A T BrüngerG L Warren
Aug 17, 1999·Progress in Molecular and Subcellular Biology·A Kornberg
Aug 17, 1999·Progress in Molecular and Subcellular Biology·N F PhillipsT H Kowalczyk
Dec 11, 1999·Nucleic Acids Research·L Lo ConteC Chothia
Sep 28, 2000·Biochemical and Biophysical Research Communications·S KawaiK Murata
Jul 4, 2002·Journal of Molecular Biology·Sara CheekNick V Grishin
Aug 20, 2003·Acta Crystallographica. Section D, Biological Crystallography·Takako MukaiKousaku Murata
Jul 24, 2004·Acta Crystallographica. Section D, Biological Crystallography·Alexander W Schüttelkopf, Daan M F van Aalten
Nov 1, 1994·Acta Crystallographica. Section D, Biological Crystallography·E A Merritt, M E Murphy
Jan 1, 1997·Methods in Enzymology·Zbyszek Otwinowski, Wladek Minor

❮ Previous
Next ❯

Citations

Jun 1, 2010·Journal of Molecular Evolution·Maria S ConejoBrian G Miller
Apr 16, 2013·Journal of Industrial Microbiology & Biotechnology·Julia S Martín del CampoY-H Percival Zhang
Oct 20, 2005·Journal of Bioscience and Bioengineering·Shigeyuki KawaiKousaku Murata
Apr 9, 2008·Bioscience, Biotechnology, and Biochemistry·Shigeyuki Kawai, Kousaku Murata
Nov 10, 2013·Bioscience, Biotechnology, and Biochemistry·Mai KoideTadashi Eguchi
May 6, 2006·Journal of Molecular Biology·Dirk Grueninger, Georg E Schulz
Oct 17, 2014·Microbiology·Friederike KlemkeThomas Volkmer
Mar 4, 2017·Trends in Biotechnology·Roland WohlgemuthWolfgang Streit
Aug 2, 2005·Biochemical and Biophysical Research Communications·Jungdon BaeDae-Sil Lee
Dec 7, 2013·Acta Crystallographica. Section D, Biological Crystallography·Magdalena SchacherlUlrich Baumann
Mar 28, 2009·Proteins·Yan Yuan Tseng, Wen-Hsiung Li
Jun 3, 2005·The Journal of Biological Chemistry·André SchiefnerWinfried Boos
Oct 26, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Jevgenia Zilberman-RudenkoOwen J T McCarty
Jun 5, 2013·The Journal of Biological Chemistry·Pedro ArêdeF Xavier Gomis-Rüth
Oct 12, 2021·Proceedings of the Japan Academy. Series B, Physical and Biological Sciences·Kousaku Murata

❮ Previous
Next ❯

Related Concepts

Related Feeds

ASBMB Publications

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.