PMID: 16522188Mar 9, 2006Paper

Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom Agrocybe aegerita

Protein and Peptide Letters
Na YangDa Cheng Wang

Abstract

An antitumour lectin named AAL has been purified from the fruiting body of edible mushroom Agrocybe aegerita. In addition to having a distinct bioactivity, AAL shows strong inhibition effects on human and mouse tumour cells. It has been shown that AAL exerts its antitumour effects via apoptosis-induction. AAL and AAL-lactose complex have been crystallized and their diffraction data were collected with resolution of 2.6 A and 3.0 A, respectively. Both crystals belong to space group P 6122 with unit cell parameters a = 123.98 A, b = 123.98 A, c = 56.86 A, alpha= beta=90 degrees, gamma = 120 degrees and a = 123.69 A, b = 123.69 A, c = 56.64 A, alpha = beta = 90 degrees, gamma = 120 degrees, respectively.

Citations

Apr 10, 2015·International Journal of Molecular Sciences·Mohamed Ali Abol HassanJoe Tiralongo
Nov 2, 2015·Applied Microbiology and Biotechnology·Jerica SabotičMarkus Künzler
Dec 6, 2016·International Journal of Molecular Sciences·Yuan-Ping LuBao-Gui Xie
Jan 7, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Senjam Sunil SinghTzi Bun Ng
Jul 21, 2017·Scientific Reports·Meina HeYoumin Kang
Jul 23, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jiao-Jiao ZhangHua-Bin Li

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