Crystallization and X-ray crystallographic analysis of human STAT1

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
Xiang Mao, Xiaomin Chen

Abstract

Unphosphorylated human STAT1 (1-683) has been crystallized in the presence of a phosphopeptide derived from the alpha-chain of human interferon gamma (IFNgamma) receptor. A complete data set has been collected from a KAu(CN)2-derivatized and dehydrated crystal. The crystal belonged to space group P6(1)22, with unit-cell parameters a = b = 102.6, c = 646.5 A, alpha = beta = 90, gamma = 120 degrees.

References

Jan 1, 1995·Annual Review of Biochemistry·C Schindler, J E Darnell
Jul 2, 1998·Biochemical and Biophysical Research Communications·U NovakL Paradiso
Aug 28, 1999·The Journal of Biological Chemistry·M I NdubuisiP B Sehgal
Sep 5, 2002·Nature Reviews. Molecular Cell Biology·David E Levy, J E Darnell
Jan 23, 2003·Protein Science : a Publication of the Protein Society·Xiaomin ChenJohn Kuriyan
Feb 11, 2003·Structure·Begoña HerasJennifer L Martin
Jul 2, 2003·The Journal of Biological Chemistry·Jutta BraunsteinChristian Schindler
Jan 6, 2004·Nature Immunology·Naruhisa OtaKenneth M Murphy
Apr 1, 2004·Molecular Cell·Montserrat Soler-LopezChristoph W Müller
Mar 23, 2005·Molecular Cell·Xiang MaoXiaomin Chen

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Citations

Apr 11, 2012·International Journal of Molecular Sciences·Irene Russo KraussAntonello Merlino
Dec 6, 2012·Insect Biochemistry and Molecular Biology·Yan ZhangQingyou Xia
Apr 12, 2013·Archives of Insect Biochemistry and Physiology·Yong-Gang HuGui-Qin Shi
Feb 18, 2010·Biochimie·Imen Najjar, Remi Fagard
Oct 7, 2014·General and Comparative Endocrinology·Guanwang ShenQingyou Xia
Mar 5, 2017·The Journal of Biological Chemistry·Ryoji FujikiOsamu Ohara

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