Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
Pablo Guardado-CalvoMark J van Raaij

Abstract

The porcine adenovirus NADC-1 isolate, a strain of porcine adenovirus type 4, has a fibre with an atypical architecture. In addition to a classical virus attachment region, shaft and head domains, it contains an additional galectin like domain C-terminal to the head domain and connected to the head domain by a long RGD-containing loop. The galectin-like domain contains two putative carbohydrate-recognition domains. The head and galectin-like domains have been independently crystallized. Diffraction data have been obtained to 3.2 angstrom resolution from crystals of the head domain and to 1.9 angstrom resolution from galectin-like domain crystals.

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Citations

Aug 6, 2010·Journal of Virology·Pablo Guardado-CalvoMark J van Raaij
Feb 3, 2012·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Carmela Garcia-Doval, Mark J van Raaij

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