Crystallography on a chip

Acta Crystallographica. Section D, Biological Crystallography
Arash Zarrine-AfsarR J Dwayne Miller

Abstract

A new chip-based crystal-mounting approach for rapid room-temperature data collection from numerous crystals is described. This work was motivated by the recent development of X-ray free-electron lasers. These novel sources deliver very intense femtosecond X-ray pulses that promise to yield high-resolution diffraction data of nanocrystals before their destruction by radiation damage. Thus, the concept of `diffraction before destruction' requires rapid replenishment of the sample for each exposure. The chip promotes the self-assembly of an array of protein crystals on a surface. Rough features on the surface cause the crystals to adopt random orientations, allowing efficient sampling of reciprocal space.

References

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Dec 23, 2010·Analytical Chemistry·Arash Zarrine-AfsarR J Dwayne Miller
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Citations

Oct 13, 2015·Acta Crystallographica. Section D, Biological Crystallography·Thomas D MurrayJames M Berger
Apr 9, 2014·Advanced Materials·Ermanno MieleFrancesco De Angelis
Dec 9, 2014·Journal of Applied Crystallography·Sarah L PerryZhong Ren
Apr 7, 2016·Acta Crystallographica. Section D, Structural Biology·Ulrich ZanderJosé Antonio Márquez
Sep 4, 2015·The Review of Scientific Instruments·Wesley D RobertsonR J Dwayne Miller
Jan 23, 2016·Structural Dynamics·C MuellerR J Dwayne Miller
Aug 28, 2012·Current Opinion in Structural Biology·Ilme Schlichting, Jianwei Miao
Jul 7, 2015·Acta Crystallographica. Section F, Structural Biology Communications·Ashtamurthy S PawateSarah L Perry
Jan 23, 2016·Structural Dynamics·Valérie PanneelsGebhard Schertler
May 7, 2015·Acta Crystallographica. Section D, Biological Crystallography·Nicolas CoquelleJacques Philippe Colletier
Jun 16, 2014·Current Opinion in Structural Biology·Geoffrey K Feld, Matthias Frank
Feb 11, 2015·Acta Crystallographica. Section D, Biological Crystallography·Sabine BothaR Bruce Doak
Jun 1, 2016·Lab on a Chip·Shuo SuiSarah L Perry
Aug 5, 2016·Acta Crystallographica. Section D, Structural Biology·Saeed OghbaeyR J Dwayne Miller
Aug 5, 2016·Acta Crystallographica. Section D, Structural Biology·Helen Mary GinnDavid Ian Stuart
Apr 5, 2017·Acta Crystallographica. Section D, Structural Biology·Robin L OwenHenrike M Mueller-Werkmeister
Jun 20, 2017·Nature Methods·Philip RoedigAlke Meents
Jun 29, 2018·Lab on a Chip·Zhong RenXiaojing Yang
Mar 2, 2019·Acta Crystallographica. Section D, Structural Biology·Marie Luise Grünbein, Gabriela Nass Kovacs
Oct 11, 2017·IUCrJ·Masaki YamamotoTakashi Kumasaka
Oct 6, 2018·Acta Crystallographica. Section D, Structural Biology·R Bruce DoakIlme Schlichting
Mar 15, 2019·IUCrJ·Jennifer L WiermanAaron D Finke
Mar 11, 2020·Journal of Synchrotron Radiation·Pedram MehrabiR J Dwayne Miller
Apr 14, 2020·Journal of Applied Crystallography·Donghyeon LeeJaehyun Park
Nov 11, 2020·Biochemical Society Transactions·Tristan O C KwanIsabel Moraes
Aug 11, 2017·ACS Applied Materials & Interfaces·Manuela OliverioFrancesco De Angelis
Sep 3, 2021·Acta Crystallographica. Section D, Structural Biology·Isabelle MartielCelestino Padeste
Jan 5, 2022·Acta Crystallographica. Section D, Structural Biology·Eike C SchulzPedram Mehrabi

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