Crystalloids of actin-like filaments in the Sertoli cell of the swine testis

The Anatomical Record
Y ToyamaH Holtzer

Abstract

Normal swine testes, congenital cryptorchid swine testes, and normal human tests were exposed to HMM (heavy meromyosin) after either glycerination or saponin treatment in order to determine whether the fine filaments composing the crystalloids in the Sertoli cells of the cryptorchid swine testes bind HMM to form arrowhead complexes. Short bundles of microfilaments observed in the basal part of the Sertoli cells in both normal and cryptorchid testes also bind HMM. Similar bundles of HMM-bound filaments are observed in the vicinity of spermatocytes. The periodicity of the arrowhead complexes is about 35 nm, and all arrowheads on a given filament point in the same direction. In addition, the polarity of the HMM-bound filaments in a given crystalloid or bundle is uni-directional. A mechanism for the formation of the swine crystalloids has been strongly support this hypothesis. Fine filaments of Charcot-Boettcher's crystalloid in human Sertoli cells did not bind HMM. Therefore the fine filaments of the human crystalloid are not actin-like in nature.

References

Apr 12, 2003·Anatomical Science International·Yoshiro ToyamaShigeki Yuasa
Sep 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J CroopH Holtzer
Nov 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·Y ToyamaH Holtzer
Apr 1, 1981·Ultrastructural Pathology·P B MarcusJ H Martin

Citations

Oct 1, 1977·Biology of Reproduction·M Dym, J C Cavicchia
Feb 9, 1977·Cell and Tissue Research·Y Toyama
Jan 1, 1971·Journal of Ultrastructure Research·A R SohvalJ Churg
Sep 1, 1968·The Journal of Cell Biology·H IshikawaH Holtzer
Jan 1, 1966·Zeitschrift für Zellforschung und mikroskopische Anatomie·T Nagano
Dec 1, 1963·Journal of Ultrastructure Research·S R BAWA

Related Concepts

Saponin
Benign Neoplasm of Testis
Cryptorchidism
Isoactin
Neoplasm of Uncertain or Unknown Behavior of Testis
Actins
Complex (molecular entity)
Crystalloid
Structure of Sertoli Cell
Inferior Colliculus

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