CSA: comprehensive comparison of pairwise protein structure alignments.

Nucleic Acids Research
Inken WohlersGunnar W Klau

Abstract

CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contact map overlap, PAUL, DALI and MATRAS. These and additional, uploaded alignments are compared using a number of quality measures and intuitive visualizations. CSA brings new insight into the structural relationship of the protein pairs under investigation and is a valuable tool for studying structural similarities. It is available at http://csa.project.cwi.nl.

References

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Citations

Jul 19, 2012·Proteins·Noël Malod-DogninFrédéric Cazals
May 25, 2013·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Inken WohlersGunnar W Klau
Oct 7, 2016·Algorithms for Molecular Biology : AMB·S SrivastavaA Rai
Jan 8, 2017·Bioinformatics·Frédéric Cazals, Tom Dreyfus

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Software Mentioned

dali
iHOP
CSA
dalix
cmo
Jmol
Biopython package
Python Imaging Library
CSA ( Comparative Structural Alignment )
DSSP

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