PMID: 15235231Jul 6, 2004Paper

CSF flow quantification of the cerebral aqueduct in normal volunteers using phase contrast cine MR imaging

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Jeong Hyun LeeChoong Gon Choi

Abstract

To evaluate whether the results of cerebrospinal fluid (CSF) flow quantification differ according to the anatomical location of the cerebral aqueduct that is used and the background baseline region that is selected. The CSF hydrodynamics of eleven healthy volunteers (mean age = 29.6 years) were investigated on a 1.5 T MRI system. Velocity maps were acquired perpendicular to the cerebral aqueduct at three different anatomical levels: the inlet, ampulla and pars posterior. The pulse sequence was a prospectively triggered cardiac-gated flow compensated gradient-echo technique. Region-of-interest (ROI) analysis was performed for the CSF hydrodynamics, including the peak systolic velocity and mean flow on the phase images. The selection of the background baseline regions was done based on measurements made in two different areas, namely the anterior midbrain and temporal lobe, for 10 subjects. The mean peak systolic velocities showed a tendency to increase from the superior to the inferior aqueduct, irrespective of the background baseline region, with the range being from 3.30 cm/sec to 4.08 cm/sec. However, these differences were not statistically significant. In the case of the mean flow, the highest mean value was observed at the...Continue Reading

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