CT and MRI features of undifferentiated carcinomas with osteoclast-like giant cells of the pancreas: a case series

Abdominal Radiology
Yoshihiko FukukuraTakashi Yoshiura

Abstract

The purpose of this case series was to describe computed tomography (CT) and magnetic resonance imaging (MRI) features of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas. Institutional ethics review board approval was obtained, and informed consent was waived for this case series. We reviewed CT and MRI of patients with pathologically confirmed undifferentiated carcinoma with osteoclast-like giant cells of the pancreas found in the medical records of our hospital between 2006 and 2016. Seven patients (3 males and 4 females; age, 59-82 years (mean, 71)) with confirmation by surgical resection (n = 3) or biopsy (n = 4) were identified. They underwent CT (n = 7) and MRI (n = 6). The tumors 26-83 mm in diameter (mean, 44 mm) were located in the head (n = 4) or body (n = 3) of the pancreas. They were demonstrated as lower attenuation areas relative to the adjacent pancreas on CT images obtained in both pancreatic and portal vein phases (n = 7) with a well-defined smooth margin (n = 5). They were demonstrated as hypointense areas relative to the pancreas on T2-weighted images (n = 4) and T2*-weighted images (n = 4) and diffusion-weighted images (n = 3). They contained hemosiderin deposits on histology (n =...Continue Reading

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Citations

Jul 4, 2019·Journal of Medical Imaging and Radiation Oncology·Kousei IshigamiHiroshi Honda
Jul 18, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Khoschy SchawkatKoenraad J Mortele
Sep 4, 2020·World Journal of Gastrointestinal Oncology·Monica NigerMaria Di Bartolomeo
Apr 21, 2020·Diagnostic and Interventional Imaging·R AldhaheriP Soyer
Mar 23, 2021·Frontiers in Oncology·Pieter DemetterLaurine Verset

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