CT and MRI in haemolytic uraemic syndrome with central nervous system involvement: distribution of lesions and prognostic value of imaging findings

Pediatric Radiology
Marc SteinbornHelmut Hahn

Abstract

Central nervous system (CNS) involvement is a common complication in haemolytic uraemic syndrome (HUS). Various imaging findings have been described, mostly as case reports. Although there are a few retrospective studies on larger patient groups there is no report that focuses on MRI. To analyse the CT and MRI studies of patients with neurological complications of HUS, to describe the typical imaging findings, and to evaluate their predictive character with regard to follow-up examinations and clinical outcome. Of 57 patients with clinically proven HUS who were referred to our hospital between 1995 and 2003, 17 had signs of serious CNS involvement and 10 underwent neuroimaging. Nine MRI and seven CT studies were performed in the acute phase and five MRI and two CT studies were done for follow-up. In six patients, pathological imaging findings were seen on CT or MRI performed in the acute phase of the disease whereas CT and MRI scans were completely normal in four patients. All patients with positive imaging findings had pathological changes within the basal ganglia. Additional findings were seen in the thalami (n=2), cerebellum (n=2) and brain stem (n=1). On follow-up imaging performed in five cases, the pathological imaging fi...Continue Reading

Citations

Dec 1, 2012·Pediatric Radiology·Carlo Cosimo QuattrocchiBruno Bernardi
Feb 19, 2009·Journal of Neurology·Joseph Ferrara, Joseph Jankovic
Aug 18, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Bérengère KoehlPatrick Niaudet
Aug 30, 2008·The Journal of Infectious Diseases·Fumiko ObataTom G Obrig
Jun 30, 2010·Antimicrobial Agents and Chemotherapy·Colleen Marie McGannonAlison Ann Weiss
Jul 30, 2011·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Lars KrogvoldHans Jacob Bangstad
May 26, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Sylvie NathansonGeorges Deschênes
Jan 17, 2012·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C AmourouxD Morin
Sep 25, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Dineke WestraNicole C A J van de Kar
Aug 8, 2014·Clinical and Experimental Nephrology·Takashi IgarashiUNKNOWN Study group for establishing guidelines for the diagnosis and therapy of hemolytic uremic syndrome
Apr 29, 2011·Pediatrics and Neonatology·Shih-Yu ChenYu-Tsun Su
Jan 24, 2012·Journal of Neuroradiology. Journal De Neuroradiologie·I Hasni BouraouiK Tlili Graeiss
Nov 29, 2011·Clinical Radiology·T BoppelA Seitz
Jun 6, 2009·Microbial Pathogenesis·Jun FujiiShin-ichi Yoshida
Jul 21, 2015·Journal of the Neurological Sciences·Julia KrämerSven G Meuth
Jan 16, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Ichiro KamiokaUNKNOWN Japanese Society for Pediatric Nephrology
Apr 18, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Takahide TeramotoNaomi Kondo
Feb 21, 2013·Annals of Neurology·Sven G MeuthHans-Christian Pape
Nov 5, 2014·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Krisztina RusaiThomas Mueller-Sacherer
May 9, 2007·Current Problems in Pediatric and Adolescent Health Care·Abiodun A OmolojaElizabeth Jackson
Sep 25, 2014·Frontiers in Pediatrics·Johannes HoferThomas Giner
Jul 23, 2016·Hematology/oncology Clinics of North America·Irina FilatovaSangam Kanekar
Jun 30, 2016·Polish journal of radiology·Abdussamet BaturMehmet Deniz Bulut
Nov 24, 2011·AJR. American Journal of Roentgenology·Paritosh C KhannaDennis W W Shaw
Apr 28, 2012·Brain : a Journal of Neurology·Tim MagnusChristian Gerloff
Jul 7, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Lucía Dieste-PérezTijs J Tobias
Dec 17, 2008·Journal of Child Neurology·Irene ToldoAnna Maria Laverda
Feb 5, 2011·AJNR. American Journal of Neuroradiology·T N EllchukA G Osborn
Dec 14, 2017·The New England Journal of Medicine·Florian S EichlerOtto Rapalino
May 25, 2016·Insights Into Imaging·Chandan KakkarAnkur Arora
Sep 6, 2017·Emergency Radiology·Alok A BhattJeevak Almast
Nov 4, 2015·Antimicrobial Agents and Chemotherapy·Romina J Fernandez-BrandoDavid L Gally
Aug 29, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jacobien C VerhaveNicole C A J van de Kar
Sep 23, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kathrin BuderGiuseppina Spartà
Jan 12, 2013·AJNR. American Journal of Neuroradiology·M WengenrothR Bruening
Mar 24, 2021·Journal of Thrombosis and Thrombolysis·Erika L Weil, Alejandro A Rabinstein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

© 2021 Meta ULC. All rights reserved