CT and MRI of experimentally induced mesenteric ischemia in a porcine model

Journal of Computer Assisted Tomography
H M KleinR W Günther

Abstract

Our goal was to assess the value of CT and MRI for the detection of bowel wall changes in experimentally induced mesenteric ischemia. in 18 female pigs, a percutaneous embolization of the superior mesenteric artery was performed with buthyl-2-cyanoacrylate and Lipiodol (1:1) (experimental group). In six animals, only diagnostic imaging and histologic evaluation were performed (control group). CT was carried out 3, 6, and 12 h after occlusion. Incremental CT (1 s scan time, 5 mm slice thickness, 7 mm increment, 120 kV/290 mAs) and spiral CT (slice thickness 5 mm, pitch 1.5, 120 kV/165 mA) were performed pre and post contrast injection (Somatom Plus/Siemens). Serial CT was carried out after intravenous contrast injection (1 ml/kg, 2 ml/s). MRI (Magnetom 1.5 T; Siemens) was performed with T1 (pre and post 0.01 mmol/kg Gd-DTPA; Magnevist; Schering, Germany), T2, and proton density images in axial orientation. Slice thickness was 3 mm and slice gap 1 mm. Additionally, a T1-weighted GE sequence (multislice FLASH 2D) was obtained in dynamic technique (before and 30, 60, and 90 s after contrast agent injection) with a slice thickness of 5 mm. Biometrical monitoring included blood pressure, heart frequency, blood cell count, electrolyte...Continue Reading

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Citations

Apr 20, 2004·Journal of Computer Assisted Tomography·Mi Young KimJeong Soo Suh
Dec 7, 2013·BMC Surgery·Alfonso ReginelliRoberto Grassi
Nov 5, 2013·World Journal of Gastroenterology : WJG·Luca SabaRoberto Grassi
Feb 7, 2015·Translational Research : the Journal of Laboratory and Clinical Medicine·Liara M GonzalezAnthony T Blikslager
Dec 10, 2003·Radiologic Clinics of North America·Ivan Pedrosa, Neil M Rofsky
Nov 22, 2014·American Journal of Physiology. Gastrointestinal and Liver Physiology·Liara M GonzalezAnthony T Blikslager

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