CT Assessment of Myocardial Perfusion and Fractional Flow Reserve

Progress in Cardiovascular Diseases
Edward HultenRon Blankstein

Abstract

Coronary computed tomography angiography (CTA) offers a non-invasive method to detect coronary plaque and stenosis. However, to date, CTA has been most useful as a method of ruling out coronary artery disease (CAD) among patients with low to intermediate pretest probability of significant CAD. The reduced specificity of CTA for detecting physiologically significant stenosis is a known limitation of this technique, particularly since some patients require additional functional testing following CTA. Therefore, intense interest has focused on the development of methods to determine the functional significance of anatomical lesions identified by CTA. This article will discuss two emerging methods: stress myocardial perfusion imaging using CT, or CT perfusion, and computer simulation of fractional flow reserve.

References

May 1, 1985·Journal of the American College of Cardiology·R M CaliffG S Wagner
Nov 17, 2007·Investigative Radiology·Richard T GeorgeAlbert C Lardo
Jan 16, 2009·The New England Journal of Medicine·Pim A L ToninoUNKNOWN FAME Study Investigators
Apr 1, 2009·Journal of Cardiovascular Computed Tomography·Ron BlanksteinRicardo C Cury
Jul 18, 2009·Annals of Biomedical Engineering·H J KimC A Taylor
Sep 12, 2009·Journal of the American College of Cardiology·Ron BlanksteinRicardo C Cury
Nov 26, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·David R OkadaRicardo C Cury
Jun 19, 2010·Annals of Biomedical Engineering·H J KimC A Taylor
Jul 14, 2010·Journal of the American College of Cardiology·Jersey ChenBrahmajee K Nallamothu
Dec 15, 2010·Journal of the American College of Cardiology·Edward A HultenTodd C Villines
Dec 8, 2011·Journal of Cardiovascular Computed Tomography·Brian B GhoshhajraRicardo C Cury
Aug 28, 2012·JAMA : the Journal of the American Medical Association·James K MinLaura Mauri
Aug 29, 2012·The New England Journal of Medicine·Bernard De BruyneUNKNOWN FAME 2 Trial Investigators
Dec 25, 2012·Current Cardiology Reports·Gilat L GrunauJonathon Leipsic
Feb 15, 2014·World Journal of Cardiology·Joel Hernandez, Raul Moreno
Oct 18, 2014·Journal of the American College of Cardiology·Nils P JohnsonK Lance Gould
Nov 5, 2014·Circulation·Reza FazelUNKNOWN American Heart Association Council on Quality of Care and Outcomes Research, Council on Clinical Cardiology, and Council on
Jan 17, 2015·JACC. Cardiovascular Imaging·Amir AhmadiJagat Narula

❮ Previous
Next ❯

Citations

Feb 13, 2016·The British Journal of Radiology·Erica MaffeiFilippo Cademartiri
Oct 18, 2015·Journal of the American College of Cardiology·Edward Hulten, Marcelo F Di Carli
Jul 19, 2016·European Journal of Radiology·Kwang Nam JinU Joseph Schoepf
Oct 27, 2016·Current Treatment Options in Cardiovascular Medicine·Gianluca PontoneMauro Pepi
May 24, 2017·European Heart Journal Supplements : Journal of the European Society of Cardiology·Francesco SecchiFrancesco Sardanelli

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.